Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14996664 | 0.74 | POLB (0.54) | MAPK14MAPK13CSNK1DCSNK1EMAPK12 | |
| SCHEMBL3262693 | 0.72 | ATM (0.42) | ATMCNR1CNR2MAP4K4PDE4D | |
| SCHEMBL12859255 | 0.71 | MAPK13 (0.41) | MAPK14MAPK13CSNK1DCSNK1EMAPK12 | |
| SCHEMBL12871764 | 0.70 | KCNH2 (0.41) | MAPK14MAPK13CSNK1DCSNK1EMAPK12 | |
| SCHEMBL17437098 | 0.69 | POLB (0.51) | MAPK14MAPK13CSNK1DCSNK1EMAPK12 | |
| SCHEMBL5258392 | 0.69 | MAPK13 (0.74) | MAPK14MAPK13CSNK1DCSNK1EMAPK12 | |
| SCHEMBL24752005 | 0.68 | ADORA2A (0.33) | ADORA2AADORA1MAPT | |
| SCHEMBL25731600 | 0.68 | TGFBR1 (0.54) | ATMMAPK14TGFBR1ADORA3ADORA2A | |
| SCHEMBL19207144 | 0.68 | SMN1; SMN2 (0.47) | CSNK1DCSNK1EPDE7ABRAFNPC1 | |
| SCHEMBL21051591 | 0.67 | ESR2 (0.41) | MAPK14MAPK13CSNK1DCSNK1EMAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |