Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethanolamine SCHEMBL5909029 | 1.00 | ALDH1A1 (0.46) | ALDH1A1TSHRL3MBTL1CYP2C19MEN1 | |
| Diethanolamine SCHEMBL7696519 | 0.96 | ALDH1A1 (0.43) | ALDH1A1TSHRL3MBTL1CYP2C19MEN1 | |
| Diethanolamine SCHEMBL28366975 | 0.90 | ALDH1A1 (0.38) | ALDH1A1TSHRL3MBTL1CYP2C19MEN1 | |
| Diethanolamine SCHEMBL827925 | 0.89 | ALDH1A1 (0.42) | ALDH1A1TSHRL3MBTL1CYP2C19MEN1 | |
| Diethanolamine SCHEMBL8083507 | 0.89 | ALDH1A1 (0.42) | ALDH1A1TSHRL3MBTL1CYP2C19MEN1 | |
| Diethanolamine SCHEMBL2325998 | 0.88 | — | — | |
| Diethanolamine SCHEMBL23363665 | 0.88 | TSHR (0.36) | ALDH1A1TSHRL3MBTL1CYP2C19MEN1 | |
| Diethanolamine SCHEMBL5843119 | 0.88 | — | — | |
| Diethanolamine SCHEMBL5307430 | 0.88 | TSHR (0.36) | ALDH1A1TSHRL3MBTL1CYP2C19MEN1 | |
| Diethanolamine SCHEMBL8930798 | 0.88 | TSHR (0.36) | ALDH1A1TSHRL3MBTL1CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114284441-A | Monomer self-polymerization assisted synthesis perovskite solar cell and preparation method thereof | 中国海洋大学 | 2022-04-05 | — | — | CN | claimed |
| CN-112143438-B | Preparation method of hydrolysis-resistant polyurethane adhesive with weather resistance | 浙江圣腾胶业股份有限公司 | 2021-04-13 | — | — | CN | claimed |
| CN-110106032-B | Automobile paint surface cleaning and repairing agent and preparation method thereof | 广州市众道汽车有限公司 | 2021-02-12 | — | — | CN | claimed |
| CN-112143438-A | Preparation method of hydrolysis-resistant polyurethane adhesive with weather resistance | 钟雨玲 | 2020-12-29 | — | — | CN | claimed |
| CN-111620864-A | Heterocyclic compound, application thereof and pharmaceutical composition containing same | 苏州信诺维医药科技有限公司 | 2020-09-04 | — | — | CN | claimed |
| CN-111620865-A | Heterocyclic compound, application thereof and pharmaceutical composition containing same | 苏州信诺维医药科技有限公司 | 2020-09-04 | — | — | CN | claimed |
| CN-110156772-B | Heterocyclic compound, application thereof and pharmaceutical composition containing same | 苏州信诺维医药科技有限公司 | 2020-08-07 | — | — | CN | claimed |
| CN-110911506-A | Rare earth Er-doped high-stability all-inorganic perovskite solar cell and preparation method thereof | 南京大学 | 2020-03-24 | — | — | CN | claimed |
| CN-104420204-B | A kind of carbon fiber water soluble epoxy sizing agent | 济南大学 | 2016-08-10 | — | — | CN | claimed |
| CN-101744890-A | Method for refining hypericin in hypericum perfortum extract | SHANGHAI SIAI MEIWEI TECHNOLOG | 2010-06-23 | — | — | CN | claimed |
| CN-1375354-A | Photocatalytic chemical reactor with surface TiO2 film and its making process | UNIV TIANJIN (CN) | 2002-10-23 | — | — | CN | claimed |
| CN-117778020-A | Washing oil composition suitable for repairing thickened oil polluted soil, preparation method and application thereof, and method for repairing thickened oil polluted soil | 中国石油化工股份有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-113832472-B | Wax removing water and application and preparation method thereof | 东莞市岩奥新材料有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-114276559-B | Water-based epoxy resin emulsion for asphalt pavement pre-curing wearing layer and preparation method thereof | 山西省交通新技术发展有限公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-114805399-A | JAK1 inhibitor and preparation method thereof | 成都先导药物开发股份有限公司 | 2022-07-29 | — | — | CN | disclosed |
| US-6099588-A | IN A SODIUM HYDROXIDE, POTASSIUM HYDROXIDE, CALCIUM HYDROXIDE OR AMMONIUM HYDROXIDE ALKALI-CONTAINING ALCOHOL SOLUTION FOLLOWED BY A PROTEASE CONTAINING AQUEOUS SOLUTION; IMPROVED SHRINK RESISTANCE | NOVO NORDISK BIOCHEM NORTH AMERICA, INC. (US) | 2000-08-08 | — | — | US | disclosed |
| US-4421739-A | SUNTAN LOTION | L'OREAL (FR) | 1983-12-20 | — | — | US | disclosed |
| US-4250097-A | (7-METHYL(2-HYDROXYETHYL)AMINO)SULFONYLXANTHONE-2-CARBOXYLIC ACID; ENZYME INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1981-02-10 | — | — | US | disclosed |
| US-4232040-A | XANTHONE CARBOXYLIC ACIDS | SYNTEX (U.S.A.) INC. (US) | 1980-11-04 | — | — | US | disclosed |
| US-3963662-A | FILMS, MEMBRANES, FILTERS, DIALYSIS | MARUZEN OIL CO. LTD. (JA) | 1976-06-15 | — | — | US | disclosed |