Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 4/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | ODC1 | P11926 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3263711 | 1.00 | FDPS (0.38) | FDPSPDE3AODC1LMNABLM | |
| SCHEMBL3224863 | 0.96 | FDPS (0.39) | FDPSPDE3AODC1LMNABLM | |
| SCHEMBL3224821 | 0.96 | FDPS (0.39) | FDPSPDE3AODC1LMNABLM | |
| SCHEMBL3209111 | 0.82 | FOLH1 (0.32) | BLMNFKB1 | |
| SCHEMBL3209087 | 0.82 | FOLH1 (0.32) | BLMNFKB1 | |
| SCHEMBL3260616 | 0.82 | ODC1 (0.33) | FDPSPDE3AODC1LMNABLM | |
| SCHEMBL3260620 | 0.82 | ODC1 (0.33) | FDPSPDE3AODC1LMNABLM | |
| SCHEMBL3225610 | 0.81 | — | — | |
| SCHEMBL3225649 | 0.81 | — | — | |
| SCHEMBL3200099 | 0.78 | FDPS (0.35) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | disclosed |
| EP-1979366-A2 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | Yu, Ruey J. (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007082206-A2 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J (US) | 2007-07-19 | — | — | WO | disclosed |