Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.54 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.54 |
| ▸ | IGF1R | P08069 | 3/20 | 0.54 |
| ▸ | ULK1 | O75385 | 2/20 | 0.53 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.53 |
| ▸ | SYK | P43405 | 11/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.50 |
| ▸ | MERTK | Q12866 | 1/20 | 0.50 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3265649 | 0.94 | AURKA (0.58) | AURKAAURKBIGF1RULK1ULK2 | |
| SCHEMBL2939842 | 0.85 | SYK (0.67) | AURKAAURKBIGF1RULK1ULK2 | |
| SCHEMBL20533977 | 0.83 | SYK (0.56) | AURKAAURKBIGF1RULK1ULK2 | |
| SCHEMBL20533975 | 0.83 | SYK (0.56) | AURKAAURKBIGF1RULK1ULK2 | |
| SCHEMBL30819885 | 0.83 | SYK (0.61) | AURKAAURKBIGF1RSYKFLT3 | |
| SCHEMBL21795916 | 0.83 | SYK (0.61) | AURKAAURKBIGF1RSYKFLT3 | |
| SCHEMBL4068789 | 0.81 | SYK (0.68) | AURKAAURKBIGF1RSYK | |
| SCHEMBL13648587 | 0.80 | SYK (0.69) | AURKAAURKBIGF1RSYKFLT3 | |
| SCHEMBL14498929 | 0.80 | SYK (0.69) | AURKAAURKBIGF1RSYKFLT3 | |
| SCHEMBL4070462 | 0.80 | SYK (0.69) | AURKAAURKBIGF1RSYKFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010025831-A1 | HETEROCYCLICALLY SUBSTITUTED ANILINOPYRIMIDINES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-03-11 | — | — | WO | disclosed |