Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 7/20 | 0.61 |
| ▸ | HTR2C | P28335 | 6/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.61 |
| ▸ | HTR1A | P08908 | 5/20 | 0.49 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 3/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2214196 | 0.80 | HTR2A (0.90) | HTR2AHTR2CSLC6A4HTR1ADRD2 | |
| SCHEMBL1077853 | 0.76 | HTR2A (0.72) | HTR2AHTR2CSLC6A4HTR1ADRD2 | |
| SCHEMBL2215606 | 0.76 | HTR2A (1.00) | HTR2AHTR2CSLC6A4HTR1ADRD2 | |
| SCHEMBL2215980 | 0.76 | SLC6A4 (0.75) | HTR2AHTR2CSLC6A4HTR1ADRD2 | |
| SCHEMBL2214253 | 0.75 | HTR2A (0.73) | HTR2AHTR2CSLC6A4HTR1ADRD2 | |
| SCHEMBL13399564 | 0.74 | HTR2A (0.54) | HTR2AHTR2CSLC6A4HTR1A | |
| SCHEMBL2214829 | 0.73 | HTR2A (0.83) | HTR2AHTR2CSLC6A4HTR1ADRD2 | |
| SCHEMBL2215751 | 0.70 | HTR2A (0.90) | HTR2AHTR2CSLC6A4HTR1ADRD2 | |
| SCHEMBL13398559 | 0.69 | HTR2A (0.60) | HTR2AHTR2CSLC6A4DRD2DRD3 | |
| SCHEMBL15376096 | 0.69 | CYP1A2 (0.66) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010038948-A2 | ARYLPIPERAZINE-CONTAINING PYRROLE 3-CARBOXAMIDE DERIVATIVES FOR TREATING DEPRESSIVE DISORDERS | GREEN CROSS CORPORATION (KR) | 2010-04-08 | — | — | WO | disclosed |