SCHEMBL3264497

SCHEMBL3264497

CC(c1ccc(-c2ccc(O)cc2)cc1)c1ccc(-c2ccc(O)cc2)cc1

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 10/20 0.84
ESR2 Q92731 8/20 0.84
PDCD1 Q15116 1/20 0.84
CD274 Q9NZQ7 1/20 0.84
CYP3A4 P08684 3/20 0.48
CYP17A1 P05093 1/20 0.48
CYP19A1 P11511 1/20 0.48
CYP11B1 P15538 1/20 0.48
CYP11B2 P19099 1/20 0.48
MMP3 P08254 1/20 0.48
BCL2L1 Q07817 1/20 0.48
CYP2C9 P11712 2/20 0.46
CYP2C19 P33261 2/20 0.46
LMNA P02545 1/20 0.46
CYP1A2 P05177 1/20 0.46
PGR P06401 1/20 0.46
CHRM2 P08172 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
AR P10275 1/20 0.46
CYP2D6 P10635 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6563988 1.00 ESR1 (0.84) ESR1ESR2PDCD1CD274CYP3A4
SCHEMBL26946 0.92 ESR1 (1.00) ESR1ESR2PDCD1CD274CYP3A4
SCHEMBL10593295 0.92 ESR1 (1.00) ESR1ESR2PDCD1CD274CYP3A4
Ammonia Solution, Strong SCHEMBL7989093 0.89 ESR1 (0.94) ESR1ESR2PDCD1CD274CYP3A4
Methane SCHEMBL21952131 0.89 ESR1 (0.94) ESR1ESR2PDCD1CD274CYP3A4
Biphenyl SCHEMBL8080851 0.88 ESR1 (0.73) ESR1ESR2PDCD1CD274MMP3
SCHEMBL15232906 0.84 ESR1 (0.84) ESR1ESR2PDCD1CD274CYP3A4
SCHEMBL21632799 0.84 ESR1 (0.84) ESR1ESR2PDCD1CD274CYP3A4
SCHEMBL9808121 0.84 ESR1 (0.84) ESR1ESR2PDCD1CD274CYP3A4
SCHEMBL23387529 0.84 ESR1 (0.59) ESR1ESR2PDCD1CD274CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9108357-B2 Multilayer decorative film BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-08-18 US disclosed
US-20130236719-A1 MULTILAYER DECORATIVE FILM COVESTRO DEUTSCHLAND AG (DE) 2013-09-12 US disclosed
EP-2184175-A1 THERMAL RECORDING MEDIUM Nippon Paper Industries Co., Ltd. (JP) 2010-05-12 EP disclosed
US-5128429-A Low temperature block polymerization without randomization RAYCHEM LIMITED (GB) 1992-07-07 US disclosed
EP-0154506-B1 PREPARATION OF ORGANIC POLYMERS RAYCHEM LIMITED (GB) 1992-02-05 EP disclosed
US-5077351-A PROCESS FOR THE PREPARATION OF POLYCARBONATE AND/OR POLYARYLATE BLOCK COPOLYMERS WITH POLY(ARYL ETHERS) AMOCO CORPORATION (US) 1991-12-31 US disclosed
US-4999411-A Polythioethers, polythiocarbonates, polythioamides, polythioimides RAYCHEM LIMITED (GB) 1991-03-12 US disclosed
US-4960835-A ENGINEERING THERMOPLASTICS RAYCHEM LIMITED (GB) 1990-10-02 US disclosed
US-4845179-A CONDENSATION POLYMERIZATION RAYCHEM LIMITED (GB) 1989-07-04 US disclosed
EP-0154506-A2 Preparation of organic polymers RAYCHEM LIMITED (GB) 1985-09-11 EP disclosed