Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.94 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.94 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.94 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.94 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26946 | 0.97 | ESR1 (1.00) | ESR1ESR2PDCD1CD274LMNA | |
| SCHEMBL10593295 | 0.97 | ESR1 (1.00) | ESR1ESR2PDCD1CD274LMNA | |
| Methane SCHEMBL21952131 | 0.94 | ESR1 (0.94) | ESR1ESR2PDCD1CD274LMNA | |
| SCHEMBL3264497 | 0.89 | ESR1 (0.84) | ESR1ESR2PDCD1CD274LMNA | |
| SCHEMBL21632799 | 0.89 | ESR1 (0.84) | ESR1ESR2PDCD1CD274LMNA | |
| SCHEMBL6563988 | 0.89 | ESR1 (0.84) | ESR1ESR2PDCD1CD274LMNA | |
| SCHEMBL15232906 | 0.89 | ESR1 (0.84) | ESR1ESR2PDCD1CD274LMNA | |
| SCHEMBL9808121 | 0.89 | ESR1 (0.84) | ESR1ESR2PDCD1CD274LMNA | |
| Phenol SCHEMBL21194938 | 0.87 | ESR1 (0.80) | ESR1ESR2PDCD1CD274LMNA | |
| SCHEMBL8031145 | 0.87 | ESR1 (0.80) | ESR1ESR2PDCD1CD274LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277851-B1 | ORALLY ADMINISTERED TRYPSIN-RELATED SERINE PROTEASE INHIBITORS; ANTICOAGULANTS | ADIR ET COMPAGNIE (FR) | 2001-08-21 | — | — | US | disclosed |