Serine

Serine

SCHEMBL3264996

C=CCl.N[C@@H](CO)C(=O)O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A1 P43005 4/20 0.46
GRIK1 P39086 7/20 0.45
GRIK2 Q13002 7/20 0.45
PTGS1 P23219 1/20 0.42
SLC7A11 Q9UPY5 1/20 0.42
GRM1 Q13255 2/20 0.41
GRM2 Q14416 2/20 0.41
SLC1A3 P43003 3/20 0.39
SLC1A2 P43004 3/20 0.39
GSR P00390 2/20 0.39
SLC7A5 Q01650 1/20 0.39
GRM8 O00222 1/20 0.39
GRM6 O15303 1/20 0.39
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
CYP1A2 P05177 1/20 0.39
GRM5 P41594 1/20 0.39
GRIA1 P42261 1/20 0.39
GRIA2 P42262 1/20 0.39
GRIA3 P42263 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Serine SCHEMBL5011214 0.88 SLC1A1 (0.48) SLC1A1GRIK1GRIK2PTGS1SLC7A11
Serine SCHEMBL5138193 0.88 SLC1A1 (0.48) SLC1A1GRIK1GRIK2PTGS1SLC7A11
Serine SCHEMBL438419 0.86 GRIK1 (0.48) SLC1A1GRIK1GRIK2PTGS1SLC7A11
Serine SCHEMBL21988617 0.86 LMNA (0.48) SLC1A1GRIK1GRIK2PTGS1SLC7A11
Serine SCHEMBL28554351 0.86 LMNA (0.48) SLC1A1GRIK1GRIK2PTGS1SLC7A11
Serine SCHEMBL21464138 0.86 GRIK1 (0.50) SLC1A1GRIK1GRIK2PTGS1SLC7A11
Serine SCHEMBL5604872 0.85
Serine SCHEMBL27681309 0.85
Serine SCHEMBL5604879 0.85
(D)-Serine SCHEMBL6660617 0.84 SLC1A1 (0.59) SLC1A1GRIK1GRIK2PTGS1SLC7A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4940682-A Solid catalyst component for olefin polymerization SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-07-10 US claimed
EP-0314131-A2 Solid catalyst component for olefin polymerization SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-05-03 EP claimed
JP-10230579-A None JP disclosed
EP-1988189-B1 PROCESS FOR PRODUCING HOT-DIP GALVANIZED STEEL SHEET WITH ZINC PHOSPHATE COAT NIPPON STEEL & SUMITOMO METAL CORP (JP) 2014-03-12 EP disclosed
US-8518841-B2 Stretchable nonwoven fabric and tape KURARAY CO., LTD. (JP) 2013-08-27 US disclosed
US-20100035500-A1 STRETCHABLE NONWOVEN FABRIC AND TAPE KURARAY KURAFLEX CO., LTD. (JP) 2010-02-11 US disclosed
EP-1988189-A1 PROCESS FOR PRODUCING HOT-DIP GALVANIZED STEEL SHEET WITH ZINC PHOSPHATE COAT Sumitomo Metal Industries Limited (JP) 2008-11-05 EP disclosed
JP-H10230579-A DECORATIVE SHEET DAINIPPON PRINTING CO LTD 1998-09-02 JP disclosed
EP-0592719-B1 Ball for ball game MOLTEN CORP (JP) 1996-06-12 EP disclosed
US-5380185-A Ball for ball game and molding apparatus for forming the same MOLTEN CORPORATION (JP) 1995-01-10 US disclosed
US-5306001-A Game ball MOLTEN CORPORATION (JP) 1994-04-26 US disclosed
EP-0592719-A1 Ball for ball game MOLTEN CORPORATION (JP) 1994-04-20 EP disclosed