Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 6/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19458018 | 0.73 | HSD17B3 (0.55) | HSD17B3FFAR1PLA2G2APLA2G5MEN1 | |
| SCHEMBL19457999 | 0.73 | HSD17B3 (0.55) | HSD17B3FFAR1PLA2G2APLA2G5MEN1 | |
| SCHEMBL9848140 | 0.71 | HSD17B3 (0.46) | HSD17B3MEN1ALDH1A1MAPTHTT | |
| SCHEMBL19458032 | 0.71 | HSD17B3 (0.53) | HSD17B3FFAR1PLA2G2APLA2G5MEN1 | |
| SCHEMBL25222615 | 0.68 | GAA (0.59) | HSD17B3MEN1ALDH1A1MAPTHTT | |
| SCHEMBL4382929 | 0.68 | GAA (0.59) | HSD17B3MEN1ALDH1A1MAPTHTT | |
| SCHEMBL4373141 | 0.68 | GAA (0.59) | HSD17B3MEN1ALDH1A1MAPTHTT | |
| SCHEMBL18825687 | 0.68 | GAA (0.59) | HSD17B3MEN1ALDH1A1MAPTHTT | |
| SCHEMBL10353082 | 0.68 | GAA (0.59) | HSD17B3MEN1ALDH1A1MAPTHTT | |
| SCHEMBL18825664 | 0.68 | GAA (0.59) | HSD17B3MEN1ALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010005572-A2 | ALPHA-KETO HETEROCYCLES AS FAAH INHIBITORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-01-14 | — | — | WO | disclosed |