Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 9/20 | 0.43 |
| ▸ | DAGLA | Q9Y4D2 | 5/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19458032 | 0.76 | HSD17B3 (0.53) | HSD17B3HTTMEN1ALDH1A1MAPT | |
| SCHEMBL23430581 | 0.74 | KEAP1 (0.61) | ALDH1A1 | |
| SCHEMBL19458018 | 0.74 | HSD17B3 (0.55) | HSD17B3HTTMEN1ALDH1A1MAPT | |
| SCHEMBL19457999 | 0.74 | HSD17B3 (0.55) | HSD17B3HTTMEN1ALDH1A1MAPT | |
| SCHEMBL3265016 | 0.71 | HSD17B3 (0.44) | HSD17B3HTTMEN1ALDH1A1MAPT | |
| SCHEMBL1531620 | 0.70 | GAA (0.57) | HSD17B3HTTMEN1ALDH1A1MAPT | |
| SCHEMBL26179087 | 0.70 | HPGD (0.49) | HSD17B3HTTMEN1ALDH1A1MAPT | |
| SCHEMBL1415222 | 0.70 | GAA (0.44) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL19457998 | 0.70 | HSD17B3 (0.52) | HSD17B3HTTMEN1ALDH1A1MAPT | |
| SCHEMBL3983005 | 0.69 | HSD17B3 (0.65) | HSD17B3FAAHHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414391-A2 | Aminoketone derivatives and use thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-02-27 | — | — | EP | disclosed |