SCHEMBL3265178

SCHEMBL3265178

CC(=S)OCCCCCCCCOc1ccc2c(c1)N(C)[C@@H](C(C)C)C(=O)NC(CO)C2

nearest known ligand 0.75

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PRKCD Q05655 10/20 0.60
PRKCG P05129 7/20 0.60
PRKCA P17252 7/20 0.60
PRKCB P05771 6/20 0.60
PRKCE Q02156 6/20 0.60
PRKCH P24723 4/20 0.60
PRKCQ Q04759 4/20 0.60
PRKD3 O94806 3/20 0.60
PRKCI P41743 3/20 0.60
PRKCZ Q05513 3/20 0.60
PRKD1 Q15139 3/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2534667 1.00 PRKCD (0.60) PRKCDPRKCGPRKCAPRKCBPRKCE
SCHEMBL2536962 1.00 PRKCD (0.60) PRKCDPRKCGPRKCAPRKCBPRKCE
SCHEMBL2534336 1.00 PRKCD (0.60) PRKCDPRKCGPRKCAPRKCBPRKCE
SCHEMBL2537642 0.99 PRKCD (0.58) PRKCDPRKCGPRKCAPRKCBPRKCE
SCHEMBL31662510 0.88 PRKCD (0.62) PRKCDPRKCGPRKCAPRKCBPRKCE
SCHEMBL12247582 0.88 PRKCA (0.72) PRKCDPRKCGPRKCAPRKCBPRKCE
SCHEMBL31662456 0.87 PRKCD (0.61) PRKCDPRKCGPRKCAPRKCBPRKCE
SCHEMBL3265177 0.86 PRKCD (0.58) PRKCDPRKCGPRKCAPRKCBPRKCE
SCHEMBL2534663 0.86 PRKCD (0.58) PRKCDPRKCGPRKCAPRKCBPRKCE
SCHEMBL2536959 0.86 PRKCD (0.58) PRKCDPRKCGPRKCAPRKCBPRKCE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010017272-A2 METHOD OF TREATING NEUROLOGICAL DISEASES THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2010-02-11 WO disclosed