⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10785174 | 0.80 | — | — | |
| SCHEMBL10785169 | 0.80 | — | — | |
| SCHEMBL10785993 | 0.78 | TSHR (0.37) | — | |
| SCHEMBL10785986 | 0.78 | TSHR (0.37) | — | |
| SCHEMBL10789919 | 0.77 | — | — | |
| SCHEMBL10785183 | 0.77 | MAPT (0.30) | — | |
| SCHEMBL10789908 | 0.77 | — | — | |
| SCHEMBL10790374 | 0.77 | — | — | |
| SCHEMBL10790369 | 0.77 | — | — | |
| SCHEMBL8465057 | 0.77 | ALOX15 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0135719-B1 | ALPHA-TERTIARY NITRILES, THEIR PREPARATION AND THEIR UTILIZATION AS AROMATIC COMPOUNDS | Consortium für elektrochemische Industrie GmbH (DE) | 1987-01-28 | — | — | EP | claimed |
| EP-0135719-A1 | Alpha-tertiary nitriles, their preparation and their utilization as aromatic compounds | Consortium für elektrochemische Industrie GmbH (DE) | 1985-04-03 | — | — | EP | claimed |
| US-9708370-B2 | Azapeptides as CD36 binding compounds | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2017-07-18 | — | — | US | disclosed |
| EP-2160404-B1 | AZAPEPTIDES AS CD36 BINDING COMPOUNDS | VALORISATION RECHERCHE LTD PARTNERSHIP (CA) | 2016-08-24 | — | — | EP | disclosed |
| US-20150329591-A1 | AZAPEPTIDES AS CD36 BINDING COMPOUNDS | CENTRE HOSPITALIER UNIVERSITAIRE SAINTE-JUSTINE (CA) | 2015-11-19 | — | — | US | disclosed |
| US-9115171-B2 | Azapeptides as CD36 binding compounds | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2015-08-25 | — | — | US | disclosed |
| US-20130203686-A1 | AZAPEPTIDES AS CD36 BINDING COMPOUNDS | INSERM (FR) | 2013-08-08 | — | — | US | disclosed |
| US-8435954-B2 | Azapeptides as CD36 binding compounds | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2013-05-07 | — | — | US | disclosed |
| US-20100210566-A1 | AZAPEPTIDES AS CD36 BINDING COMPOUNDS | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2010-08-19 | — | — | US | disclosed |
| EP-2160404-A1 | AZAPEPTIDES AS CD36 BINDING COMPOUNDS | UNIVERSITE DE MONTREAL (CA) | 2010-03-10 | — | — | EP | disclosed |
| WO-2008154738-A1 | AZAPEPTIDES AS CD36 BINDING COMPOUNDS | UNIVERSITE DE MONTREAL (CA) | 2008-12-24 | — | — | WO | disclosed |
| EP-0135719-B1 | ALPHA-TERTIARY NITRILES, THEIR PREPARATION AND THEIR UTILIZATION AS AROMATIC COMPOUNDS | Consortium für elektrochemische Industrie GmbH (DE) | 1987-01-28 | — | — | EP | disclosed |
| US-4625046-A | Alpha-tertiary nitriles | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1986-11-25 | — | — | US | disclosed |
| EP-0135719-A1 | Alpha-tertiary nitriles, their preparation and their utilization as aromatic compounds | Consortium für elektrochemische Industrie GmbH (DE) | 1985-04-03 | — | — | EP | disclosed |