Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1995651 | 0.83 | F2 (0.36) | IDO1CTSSSMN1; SMN2NPSR1HTT | |
| SCHEMBL1995652 | 0.82 | SCN9A (0.35) | IDO1SMN1; SMN2NPSR1HTTTP53 | |
| SCHEMBL1551683 | 0.72 | CYP3A4 (0.42) | SMN1; SMN2NPSR1HTTTP53CYP3A4 | |
| SCHEMBL1991847 | 0.71 | SMN1; SMN2 (0.40) | SMN1; SMN2NPSR1HTTTP53CYP3A4 | |
| SCHEMBL3401787 | 0.67 | F2 (0.39) | IDO1SMN1; SMN2TP53LMNAP2RX7 | |
| SCHEMBL1990364 | 0.67 | F2 (0.38) | IDO1SMN1; SMN2TP53LMNAP2RX7 | |
| SCHEMBL1551280 | 0.67 | LMNA (0.46) | SMN1; SMN2NPSR1HTTLMNATSHR | |
| SCHEMBL1551573 | 0.66 | SMN1; SMN2 (0.43) | SMN1; SMN2HTTCYP3A4LMNA | |
| SCHEMBL1551297 | 0.66 | CYP19A1 (0.38) | IDO1TP53P2RX7 | |
| SCHEMBL1551019 | 0.65 | F2 (0.36) | IDO1TP53P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010018328-A1 | AZETIDINE POLYSUBSTITUTED COMPOUNDS, PREPARATION THEREOF, AND THERAPEUTIC APPLICATION THEREOF | SANOFI-AVENTIS (FR) | 2010-02-18 | — | — | WO | claimed |