Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5533895 | 0.87 | TYR (0.50) | GABRA1GABRB2TYRRECQLTDP1 | |
| SCHEMBL5523843 | 0.80 | HIF1A (0.55) | GABRA1GABRB2TYRRECQLTDP1 | |
| SCHEMBL15071479 | 0.79 | GABRA1 (0.52) | GABRA1GABRB2TYRRECQLTDP1 | |
| SCHEMBL30336405 | 0.79 | TYR (0.58) | GABRA1GABRB2TYRRECQLTDP1 | |
| SCHEMBL5673474 | 0.79 | TYR (0.44) | GABRA1GABRB2TYRTDP1KDM4E | |
| SCHEMBL9081257 | 0.79 | TYR (0.58) | GABRA1GABRB2TYRRECQLTDP1 | |
| SCHEMBL3032916 | 0.76 | GABRA1 (0.48) | GABRA1GABRB2TYRTDP1MAPT | |
| SCHEMBL1345493 | 0.76 | TYR (0.53) | GABRA1GABRB2TYRRECQLTDP1 | |
| SCHEMBL5521901 | 0.74 | GAA (0.61) | RECQLTDP1KDM4EMAPTHIF1A | |
| SCHEMBL11804395 | 0.74 | TYR (0.56) | GABRA1GABRB2TYRTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1136886-B1 | Positive-working presensitized plate useful for preparing a lithographic printing plate | FUJIFILM CORP (JP) | 2010-05-19 | — | — | EP | disclosed |
| US-6517987-B2 | Mixture of 1,2-naphthoquinone-2-diazide-5-sulfonic acid and polymer | FUJI PHOTO FILM CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1136886-A1 | Positive-working presensitized plate useful for preparing a lithographic printing plate | Fuji Photo Film Co., Ltd. (JP) | 2001-09-26 | — | — | EP | disclosed |