Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2847319 | 0.78 | KDM4E (0.41) | KMT2AKDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL32690599 | 0.78 | KDM4E (0.39) | KMT2AKDM4EMAPTALDH1A1P2RX7 | |
| SCHEMBL13448658 | 0.78 | KDM4E (0.65) | KMT2AKDM4EMAPTALDH1A1P2RX7 | |
| SCHEMBL30388905 | 0.77 | CYP2C19 (0.47) | KMT2AKDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL13448704 | 0.77 | ALDH1A1 (0.40) | KMT2AKDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL18122821 | 0.76 | KDM4E (0.63) | KMT2AKDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL4928521 | 0.76 | KDM4E (0.38) | KMT2AKDM4EMAPTALDH1A1P2RX7 | |
| SCHEMBL9613266 | 0.74 | KDM4E (0.41) | KMT2AKDM4EALDH1A1P2RX7SMN1; SMN2 | |
| SCHEMBL1957150 | 0.74 | KDM4E (0.36) | KMT2AKDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL2838138 | 0.73 | KDM4E (0.37) | KMT2AKDM4EMAPTALDH1A1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010054024-A2 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2010-05-14 | — | — | WO | disclosed |