Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 18/20 | 0.52 |
| ▸ | ROCK1 | Q13464 | 14/20 | 0.52 |
| ▸ | CDC42BPA | Q5VT25 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13391296 | 0.78 | ROCK2 (0.52) | ROCK2ROCK1CDC42BPACYP2C9 | |
| SCHEMBL3246086 | 0.78 | ROCK2 (0.65) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3127085 | 0.71 | ROCK2 (0.91) | ROCK2ROCK1CDC42BPACYP2C9 | |
| SCHEMBL1648748 | 0.71 | ROCK2 (0.83) | ROCK2ROCK1 | |
| SCHEMBL3247361 | 0.71 | ROCK2 (0.72) | ROCK2ROCK1CDC42BPACYP2C9 | |
| SCHEMBL3247694 | 0.70 | ROCK2 (0.72) | ROCK2ROCK1CDC42BPACYP2C9 | |
| SCHEMBL3122197 | 0.70 | ROCK2 (0.91) | ROCK2ROCK1CDC42BPACYP2C9 | |
| SCHEMBL3248836 | 0.70 | ROCK2 (0.76) | ROCK2ROCK1CDC42BPACYP2C9 | |
| SCHEMBL3242192 | 0.69 | ROCK2 (0.73) | ROCK2ROCK1CDC42BPACYP2C9 | |
| SCHEMBL15995780 | 0.69 | ROCK2 (0.63) | ROCK2ROCK1CDC42BPACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | disclosed |