Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 20/20 | 0.77 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.56 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3634010 | 0.96 | DGAT1 (0.83) | DGAT1SOAT2SOAT1 | |
| Acetamide SCHEMBL28785427 | 0.92 | DGAT1 (0.79) | DGAT1SOAT2SOAT1 | |
| SCHEMBL10262363 | 0.91 | DGAT1 (0.93) | DGAT1SOAT2SOAT1 | |
| SCHEMBL3202568 | 0.90 | DGAT1 (0.73) | DGAT1SOAT2SOAT1 | |
| Propionamide SCHEMBL27796578 | 0.90 | DGAT1 (0.75) | DGAT1SOAT2SOAT1 | |
| SCHEMBL10261107 | 0.89 | DGAT1 (0.87) | DGAT1SOAT2SOAT1 | |
| SCHEMBL3205296 | 0.89 | DGAT1 (0.80) | DGAT1SOAT2SOAT1 | |
| SCHEMBL3205675 | 0.89 | DGAT1 (0.80) | DGAT1 | |
| SCHEMBL3205570 | 0.88 | DGAT1 (0.94) | DGAT1SOAT2SOAT1 | |
| SCHEMBL3205557 | 0.88 | DGAT1 (0.94) | DGAT1SOAT2SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010017040-A1 | DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | VIA PHARMACEUTICALS, INC (US) | 2010-02-11 | — | — | WO | disclosed |