Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | AHR | P35869 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL967909 | 0.79 | CYP3A4 (0.44) | CYP3A4MAPK1AHRTSHRTDP1 | |
| SCHEMBL2130360 | 0.76 | TSHR (0.60) | TSHRALDH1A1LMNACYP2A6ATM | |
| SCHEMBL16958284 | 0.76 | CYP3A4 (0.46) | CYP3A4MAPK1AHRHTTNPSR1 | |
| SCHEMBL11860346 | 0.75 | CYP3A4 (0.41) | CYP3A4MAPK1AHRHTTNPSR1 | |
| SCHEMBL20513001 | 0.75 | CYP3A4 (0.41) | CYP3A4MAPK1HTTNPSR1TSHR | |
| SCHEMBL5030228 | 0.75 | CYP3A4 (0.41) | CYP3A4MAPK1HTTNPSR1TSHR | |
| SCHEMBL348089 | 0.74 | CYP3A4 (0.62) | CYP3A4MAPK1AHRTSHRTDP1 | |
| SCHEMBL29368277 | 0.74 | CYP3A4 (0.62) | CYP3A4MAPK1AHRTSHRTDP1 | |
| SCHEMBL4452322 | 0.74 | MAPK1 (0.44) | CYP3A4MAPK1TSHRTDP1CSNK2A2 | |
| SCHEMBL6894343 | 0.74 | CYP3A4 (0.44) | CYP3A4MAPK1AHRHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0305196-B1 | Novel trisubstituted symmetrical triazines, their preparation and their use | BROMINE COMPOUNDS LTD (IL) | 1994-01-19 | — | — | EP | claimed |
| US-4977262-A | FLAME RETARDANTS FOR PLASTICS | BROMINE COMPOUNDS LIMITED (IL) | 1990-12-11 | — | — | US | claimed |
| EP-0305196-A2 | Novel trisubstituted symmetrical triazines, their preparation and their use | Bromine Compounds Ltd. (IL) | 1989-03-01 | — | — | EP | claimed |
| EP-0021519-B1 | OXYIMINO-SUBSTITUTED CYCLOPROPANE COMPOUNDS, PROCESS FOR THEIR MANUFACTURE, PESTICIDAL COMPOSITIONS AND THEIR USE AS AND IN THE MANUFACTURE OF PESTICIDES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1984-07-18 | — | — | EP | claimed |
| US-4267340-A | BACTERICIDES; SYNTHESIS OF PENICILLINS AND CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-05-12 | — | — | US | claimed |
| EP-0021519-A2 | Oxyimino-substituted cyclopropane compounds, process for their manufacture, pesticidal compositions and their use as and in the manufacture of pesticides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1981-01-07 | — | — | EP | claimed |
| EP-0021520-A1 | (Cycloalkyl)alkoxyimino-substituted cyclopropanecarboxylate esters, process for their manufacture, pesticidal compositions containing them, and their use as pesticides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1981-01-07 | — | — | EP | claimed |
| US-4237123-A | INSECTICIDES, MITICIDES | SHELL OIL COMPANY (US) | 1980-12-02 | — | — | US | claimed |
| US-4219565-A | INSECTICIDES, MITICIDES | SHELL OIL COMPANY (US) | 1980-08-26 | — | — | US | claimed |
| EP-0001682-A2 | Heterocyclic compounds and their use as pesticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-05-02 | — | — | EP | claimed |
| US-4092474-A | Cephalosporins having a metaloxy group in 3-substituent | SHIONOGI & CO., LTD. (JA) | 1978-05-30 | — | — | US | claimed |
| US-4009159-A | PENICILLINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1977-02-22 | — | — | US | claimed |
| US-20210340346-A1 | METAL FILM-COATED MOLDED RESIN ARTICLES AND PRODUCTION METHOD THEREFOR | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2021-11-04 | — | — | US | disclosed |
| CN-107417490-B | Tower type continuous photochlorination method for preparing chlorobenzyl | 方圆化工有限公司 | 2021-09-10 | — | — | CN | disclosed |
| CN-112654728-A | Resin molded article with metal film and method for producing same | 三菱工程塑料株式会社 | 2021-04-13 | — | — | CN | disclosed |
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |
| US-4091210-A | Preparation of 3-alkyl-3-cephem-4-carboxylic acid compounds from dithio isopropenyl azetidine carboxylic compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1978-05-23 | — | — | US | disclosed |
| US-4084049-A | CEPHALOSPORIN ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1978-04-11 | — | — | US | disclosed |
| US-3984397-A | CYCLIZATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-10-05 | — | — | US | disclosed |
| US-3954732-A | BACTERICIDAL PENICILLINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-05-04 | — | — | US | disclosed |