Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20513001 | 0.86 | CYP3A4 (0.41) | CYP3A4MAPK1TSHRGPR27KMT2A | |
| SCHEMBL30360858 | 0.84 | CYP3A4 (0.39) | CYP3A4MAPK1TSHRGPR27KMT2A | |
| SCHEMBL6563882 | 0.84 | CYP3A4 (0.39) | CYP3A4MAPK1TSHRGPR27KMT2A | |
| SCHEMBL29566931 | 0.80 | TSHR (0.63) | TSHRKMT2AATMLMNAALDH1A1 | |
| SCHEMBL36590 | 0.80 | TSHR (0.63) | TSHRKMT2AATMLMNAALDH1A1 | |
| SCHEMBL23318194 | 0.78 | STAT3 (0.38) | CYP3A4MAPK1TSHRKMT2AALPL | |
| SCHEMBL11406014 | 0.77 | CYP3A4 (0.43) | CYP3A4MAPK1TSHRKMT2ALMNA | |
| SCHEMBL432644 | 0.76 | TSHR (0.64) | CYP3A4MAPK1TSHRGPR27KMT2A | |
| SCHEMBL4452322 | 0.76 | MAPK1 (0.44) | CYP3A4MAPK1TSHRGPR27KMT2A | |
| SCHEMBL29886586 | 0.76 | TSHR (0.64) | CYP3A4MAPK1TSHRGPR27KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007924-A1 | SILICONE COATING COMPOSITION FOR PROTECTION FROM CATHODIC STRESS | CSL Silicones Inc. (CA) | 2008-12-31 | — | — | EP | disclosed |
| US-20070232749-A1 | Silicone coating composition for protection from cathodic stress | CSL SILICONES INC. | 2007-10-04 | — | — | US | disclosed |
| WO-2007104122-A1 | METHOD FOR PROTECTING PIPELINES AGAINST CORROSION | CSL SILICONES INC. (CA) | 2007-09-20 | — | — | WO | disclosed |
| WO-2007104121-A1 | SILICONE COATING COMPOSITION FOR PROTECTION FROM CATHODIC STRESS | CSL SILICONES INC. (CA) | 2007-09-20 | — | — | WO | disclosed |
| US-20070218211-A1 | Method for protecting pipelines against corrosion | CSL SILICONES INC. | 2007-09-20 | — | — | US | disclosed |