Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 10/20 | 0.43 |
| ▸ | ABL1 | P00519 | 4/20 | 0.43 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | HCK | P08631 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 2/20 | 0.39 |
| ▸ | CSK | P41240 | 2/20 | 0.39 |
| ▸ | EPHA3 | P29320 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23630561 | 1.00 | SRC (0.43) | SRCABL1EGFRHCKPIK3CD | |
| SCHEMBL23630541 | 0.90 | SRC (0.44) | SRCABL1EGFRHCKPIK3CD | |
| SCHEMBL32659774 | 0.90 | SRC (0.44) | SRCABL1EGFRHCKPIK3CD | |
| SCHEMBL32659762 | 0.89 | SRC (0.41) | SRCABL1EGFRHCKLCK | |
| SCHEMBL23630544 | 0.89 | SRC (0.41) | SRCABL1EGFRHCKLCK | |
| SCHEMBL23630524 | 0.81 | EGFR (0.42) | SRCEGFRKDRLCKMAPT | |
| SCHEMBL23630560 | 0.80 | SRC (0.43) | SRCEGFRKDRLCKMAPT | |
| SCHEMBL23630529 | 0.80 | LMNA (0.46) | SRCABL1EGFRKDRMAPT | |
| SCHEMBL23630563 | 0.80 | SRC (0.42) | SRCABL1EGFRHCKPIK3CD | |
| SCHEMBL32659776 | 0.80 | SRC (0.42) | SRCABL1EGFRHCKPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12522606-B2 | Modified pyrrolo- and pyrazolo-pyrimidines for prostate cancer therapy | UNIVERSITY OF WASHINGTON (US) | 2026-01-13 | — | — | US | claimed |