SCHEMBL32659880

SCHEMBL32659880

CC(C)(C)c1n[nH]c(=O)n(N)c1=O

nearest known ligand 0.68

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.33
HPGD P15428 1/20 0.32
LMNA P02545 2/20 0.31
MAPK1 P28482 1/20 0.31
KDM4E B2RXH2 1/20 0.30
TP53 P04637 1/20 0.30
HTT P42858 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9367455 0.75
SCHEMBL8011310 0.72
SCHEMBL9696181 0.69 GSK3A (0.44) GAAHPGDLMNAMAPK1KDM4E
SCHEMBL11608364 0.67 GAA (0.43) GAAHPGDLMNAMAPK1KDM4E
SCHEMBL11609881 0.65 GAA (0.40) GAAHPGDLMNAMAPK1KDM4E
SCHEMBL10505909 0.65 GAA (0.42) GAAHPGDLMNAMAPK1KDM4E
SCHEMBL10980860 0.65 GAA (0.48) GAAHPGDLMNAMAPK1KDM4E
SCHEMBL9279734 0.64
SCHEMBL6352826 0.64 GAA (0.41) GAAHPGDLMNAMAPK1KDM4E
SCHEMBL6496071 0.63 ALDH1A1 (0.32) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4679086-A1 BIOMARKER AND USE THEREOF MEIJI CO., LTD (JP) 2026-01-14 EP claimed
EP-4679086-A1 BIOMARKER AND USE THEREOF MEIJI CO., LTD (JP) 2026-01-14 EP disclosed