Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | NPC1L1 | Q9UHC9 | 3/20 | 0.43 |
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32660019 | 0.89 | ALOX15 (0.56) | NAMPTPARP1NPC1L1PADI4KMT2A | |
| SCHEMBL18976645 | 0.84 | CA1 (0.54) | NAMPTCA1CA2PARP1HDAC3 | |
| SCHEMBL32660029 | 0.83 | ABL1 (0.54) | EPHX1MEN1RAB9AKMT2A | |
| SCHEMBL32660020 | 0.83 | ABL1 (0.54) | EPHX1MEN1RAB9AKMT2A | |
| SCHEMBL31267093 | 0.80 | NAMPT (0.57) | NAMPTCA1CA2PARP1HDAC3 | |
| SCHEMBL31267054 | 0.80 | NAMPT (0.57) | NAMPTCA1CA2PARP1HDAC3 | |
| SCHEMBL25145116 | 0.79 | CA1 (0.51) | NAMPTCA1CA2PARP1HDAC3 | |
| SCHEMBL16841169 | 0.79 | CA1 (0.51) | NAMPTCA1CA2PARP1HDAC3 | |
| SCHEMBL30325458 | 0.79 | CA1 (0.51) | NAMPTCA1CA2PARP1HDAC3 | |
| SCHEMBL24185232 | 0.79 | NAMPT (0.56) | NAMPTCA1CA2PARP1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4678633-A1 | NOVEL FERROPTOSIS INHIBITORS | Universiteit Antwerpen (BE) | 2026-01-14 | — | — | EP | disclosed |