Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBFB | Q13951 | 13/20 | 0.80 |
| ▸ | METAP2 | P50579 | 7/20 | 0.61 |
| ▸ | METAP1 | P53582 | 6/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | PKM | P14618 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | MTOR | P42345 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 1/20 | 0.51 |
| ▸ | F7 | P08709 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL125118 | 1.00 | CBFB (0.80) | CBFBMETAP2METAP1NPC1PKM | |
| SCHEMBL5032550 | 0.89 | CBFB (1.00) | CBFBMETAP2METAP1NPC1PKM | |
| SCHEMBL32660767 | 0.89 | CBFB (1.00) | CBFBMETAP2METAP1NPC1PKM | |
| SCHEMBL29994214 | 0.86 | METAP2 (0.61) | CBFBMETAP2METAP1NPC1PKM | |
| SCHEMBL13675150 | 0.86 | CBFB (0.62) | CBFBMETAP2METAP1NPC1PKM | |
| SCHEMBL23704308 | 0.86 | METAP2 (0.61) | CBFBMETAP2METAP1NPC1PKM | |
| SCHEMBL124343 | 0.86 | CBFB (0.80) | CBFBMETAP2METAP1NPC1PKM | |
| SCHEMBL6616899 | 0.85 | CBFB (0.60) | CBFBMETAP2METAP1NPC1PKM | |
| SCHEMBL17525961 | 0.85 | METAP2 (0.60) | CBFBMETAP2METAP1NPC1PKM | |
| SCHEMBL19970738 | 0.84 | CBFB (0.58) | CBFBMETAP2METAP1NPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4678234-A1 | ANTAGONIST HETEROCYCLIC COMPOUNDS INVOLVED IN THE CGAS-STING ROUTE | Centre National de la Recherche Scientifique (FR) | 2026-01-14 | — | — | EP | disclosed |