Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3242963 | 0.76 | MEN1 (0.46) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL3243831 | 0.73 | KMT2A (0.44) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL3244858 | 0.71 | MAPT (0.46) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL3236813 | 0.66 | NOTUM (0.40) | MEN1KMT2ADRD2CHRNB2CHRNA7 | |
| SCHEMBL3243594 | 0.66 | NOTUM (0.40) | MEN1KMT2ADRD2CHRNB2CHRNA7 | |
| SCHEMBL3243592 | 0.66 | NOTUM (0.40) | MEN1KMT2ADRD2CHRNB2CHRNA7 | |
| SCHEMBL9294528 | 0.65 | CHRNB2 (0.53) | MEN1KMT2AALDH1A1LMNACHRNB2 | |
| SCHEMBL9294538 | 0.65 | CHRNB2 (0.53) | MEN1KMT2AALDH1A1LMNACHRNB2 | |
| SCHEMBL9294533 | 0.65 | CHRNB2 (0.53) | MEN1KMT2AALDH1A1LMNACHRNB2 | |
| SCHEMBL29618970 | 0.64 | NOTUM (0.53) | MEN1KMT2AALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2102204-B1 | NEW AMINOPYRROLO[1,2- A]INDOLE ET AMINOPYRIDAZINO[1,6-A]INDOLE DERIVATIVES, METHOD FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SERVIER LAB (FR) | 2010-05-05 | — | — | EP | disclosed |