Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 7/20 | 0.49 |
| ▸ | CES2 | O00748 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12816020 | 0.85 | CES1 (0.52) | PTPN1CES1CES2TSHRSRC | |
| SCHEMBL4002970 | 0.82 | TSHR (0.53) | CES1CES2LMNATSHRALDH1A1 | |
| SCHEMBL11536474 | 0.81 | NR4A2 (0.47) | PTPN1CES1LMNATSHRALDH1A1 | |
| SCHEMBL452703 | 0.81 | CES1 (0.49) | CES1CES2LMNATSHRSRC | |
| SCHEMBL4006883 | 0.79 | TSHR (0.42) | CES1CES2LMNATSHRALDH1A1 | |
| SCHEMBL1076574 | 0.79 | TSHR (0.50) | LMNATSHRALDH1A1HDAC1DRD2 | |
| SCHEMBL28150792 | 0.79 | HTT (0.56) | LMNATSHRALDH1A1DRD2OPRM1 | |
| SCHEMBL4929013 | 0.79 | CES1 (0.46) | CES1CES2LMNANAAASRC | |
| SCHEMBL28879634 | 0.79 | PTPN1 (0.50) | PTPN1CES1CES2TSHRSRC | |
| SCHEMBL6761557 | 0.78 | TSHR (0.49) | LMNATSHRALDH1A1HDAC1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1711542-B1 | DIRECTLY PHOTODEFINABLE POLYMER COMPOSITIONS AND METHODS THEREOF | PROMERUS LLC (US) | 2010-06-09 | — | — | EP | disclosed |
| US-7378456-B2 | Directly photodefinable polymer compositions and methods thereof | PROMERUS LLC (US) | 2008-05-27 | — | — | US | disclosed |
| EP-1711542-A2 | DIRECTLY PHOTODEFINABLE POLYMER COMPOSITIONS AND METHODS THEREOF | Promerus, LLC (US) | 2006-10-18 | — | — | EP | disclosed |
| US-20050186502-A1 | Directly photodefinable polymer compositions and methods thereof | SUMITOMO BAKELITE CO., LTD. (JP) | 2005-08-25 | — | — | US | disclosed |
| WO-2005076076-A2 | DIRECTLY PHOTODEFINABLE POLYMER COMPOSITIONS AND METHODS THEREOF | PROMERUS, LLC (US) | 2005-08-18 | — | — | WO | disclosed |