Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SCN1A | P35498 | 3/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4002970 | 0.92 | TSHR (0.53) | TSHRALDH1A1HDAC1CYP2C19HIF1A | |
| SCHEMBL8905858 | 0.91 | ALDH1A1 (0.49) | TSHRALDH1A1HDAC1CYP2C19HIF1A | |
| SCHEMBL8904807 | 0.89 | TSHR (0.47) | TSHRALDH1A1HDAC1CYP2C19HIF1A | |
| SCHEMBL504013 | 0.88 | ALDH1A1 (0.57) | TSHRALDH1A1HDAC1CYP2C19HIF1A | |
| SCHEMBL8905848 | 0.87 | ALDH1A1 (0.46) | TSHRALDH1A1HDAC1KIF11GAA | |
| SCHEMBL8903837 | 0.87 | ALDH1A1 (0.46) | TSHRALDH1A1HDAC1KIF11GAA | |
| SCHEMBL8905573 | 0.87 | ALDH1A1 (0.46) | TSHRALDH1A1HDAC1KIF11GAA | |
| SCHEMBL8905259 | 0.87 | ALDH1A1 (0.46) | TSHRALDH1A1HDAC1KIF11GAA | |
| SCHEMBL6761557 | 0.87 | TSHR (0.49) | TSHRALDH1A1HDAC1CYP2C19HIF1A | |
| SCHEMBL1131428 | 0.87 | ALDH1A1 (0.49) | TSHRALDH1A1CYP2C19HIF1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389466-B2 | Use of carboxylic acid esters as a fragrance substance | SYMRISE AG (DE) | 2013-03-05 | — | — | US | disclosed |
| EP-2274409-B1 | USE OF CARBOXYLIC ACID ESTERS AS A FRAGRANCE SUBSTANCE | SYMRISE AG (DE) | 2011-10-12 | — | — | EP | disclosed |
| US-20110104092-A1 | USE OF CARBOXYLIC ACID ESTERS AS A FRAGRANCE SUBSTANCE | SYMRISE AG (DE) | 2011-05-05 | — | — | US | disclosed |
| EP-2274409-A1 | USE OF CARBOXYLIC ACID ESTERS AS A FRAGRANCE SUBSTANCE | Symrise AG (DE) | 2011-01-19 | — | — | EP | disclosed |
| US-20100158905-A1 | COMBINATION THERAPY OF ARTHRITIS WITH TRANILAST | NUON THERAPEUTICS, INC. (US) | 2010-06-24 | — | — | US | disclosed |
| EP-1920042-B1 | PARTICLES CONTAINING PERFUME HAVING IMPROVED FRAGRANCED PROPERTIES | HENKEL AG & CO KGAA (DE) | 2010-06-23 | — | — | EP | disclosed |
| WO-2009124888-A1 | USE OF CARBOXYLIC ACID ESTERS AS A FRAGRANCE SUBSTANCE | SYMRISE GMBH & CO. KG (DE) | 2009-10-15 | — | — | WO | disclosed |
| US-5597848-A | PLATELET AGGREGATION INHIBITORS, ANTITHROMBOTIC AGENTS, ANTIASTHMATIC AGENTS, ANTIALLERGIC AGENTS | HOKURIKU SEIYAKU CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100158905-A1 | COMBINATION THERAPY OF ARTHRITIS WITH TRANILAST | PTGS2, PTGES2, PTGES | TSHR 2986/4885ALDH1A1 351/4885HDAC1 638/4885 |
| US-20110104092-A1 | USE OF CARBOXYLIC ACID ESTERS AS A FRAGRANCE SUBSTANCE | FASN, ELOVL5, ALDH16A1 | TSHR 4478/4885ALDH1A1 9/4885HDAC1 1393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.