Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.73 |
| ▸ | CSNK1A1 | P48729 | 12/20 | 0.73 |
| ▸ | IKZF2 | Q9UKS7 | 14/20 | 0.62 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.49 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27387095 | 0.94 | CRBN (0.82) | CRBNCSNK1A1IKZF2GSPT1DDB1 | |
| SCHEMBL32664820 | 0.93 | CRBN (0.74) | CRBNCSNK1A1IKZF2GSPT1DDB1 | |
| SCHEMBL27387109 | 0.88 | CRBN (0.84) | CRBNCSNK1A1IKZF2 | |
| SCHEMBL31403679 | 0.87 | CRBN (0.70) | CRBNCSNK1A1IKZF2GSPT1DDB1 | |
| SCHEMBL23980468 | 0.87 | CRBN (0.70) | CRBNCSNK1A1IKZF2GSPT1DDB1 | |
| SCHEMBL32665096 | 0.86 | CRBN (0.67) | CRBNCSNK1A1IKZF2GSPT1DDB1 | |
| SCHEMBL27387229 | 0.86 | CRBN (0.67) | CRBNCSNK1A1IKZF2GSPT1DDB1 | |
| SCHEMBL32665004 | 0.86 | CRBN (0.72) | CRBNCSNK1A1IKZF2GSPT1DDB1 | |
| SCHEMBL27387231 | 0.86 | CRBN (0.72) | CRBNCSNK1A1IKZF2GSPT1DDB1 | |
| SCHEMBL30707561 | 0.85 | CRBN (1.00) | CRBNCSNK1A1IKZF2GSPT1DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021103-A1 | IKZF2 AND CK1-ALPHA DEGRADING COMPOUNDS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021103-A1 | IKZF2 AND CK1-ALPHA DEGRADING COMPOUNDS AND USES THEREOF | IKZF1, CSNK1A1, CKS1B | CRBN 16/4885CSNK1A1 2/4885IKZF2 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.