Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.56 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 3/20 | 0.47 |
| ▸ | IDH1 | O75874 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | ABAT | P80404 | 1/20 | 0.41 |
| ▸ | HNF4A | P41235 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9348618 | 0.85 | IDO1 (0.50) | IDO1APPIDH1CYP1A2CYP2D6 | |
| SCHEMBL2977565 | 0.85 | ESR1 (0.70) | ESR1ESR2IDH1KEAP1ABAT | |
| SCHEMBL9352538 | 0.85 | IDO1 (0.58) | IDO1IDH1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL26149603 | 0.83 | CALM1 (0.57) | IDO1IDH1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL921375 | 0.81 | ESR1 (0.64) | ESR1ESR2IDH1CYP1A2KEAP1 | |
| SCHEMBL28131779 | 0.80 | IDO1 (0.46) | IDO1APPIDH1CYP1A2CYP2D6 | |
| SCHEMBL20691033 | 0.80 | IDO1 (0.46) | ESR1ESR2IDO1IDH1CYP1A2 | |
| SCHEMBL6563885 | 0.79 | IDO1 (0.52) | IDO1IDH1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL4312934 | 0.78 | ESR1 (0.74) | ESR1ESR2IDO1APPCYP2C19 | |
| Resorcinol SCHEMBL10603853 | 0.76 | ESR1 (0.70) | ESR1ESR2IDH1CYP1A2KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | ESR1 3453/4885ESR2 941/4885IDO1 3227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.