Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27860388 | 0.86 | MAPK1 (0.44) | MAPK1 | |
| SCHEMBL8227538 | 0.86 | MAPK1 (0.44) | MAPK1 | |
| SCHEMBL31688916 | 0.84 | MAPK1 (0.42) | MAPK1 | |
| SCHEMBL2030106 | 0.84 | MAPK1 (0.48) | MAPK1 | |
| SCHEMBL3271447 | 0.84 | MAPK1 (0.48) | MAPK1 | |
| SCHEMBL2028703 | 0.84 | MAPK1 (0.48) | MAPK1 | |
| SCHEMBL19053359 | 0.82 | MAPK1 (0.46) | MAPK1 | |
| SCHEMBL22060223 | 0.82 | MAPK1 (0.46) | MAPK1 | |
| SCHEMBL17992734 | 0.79 | — | — | |
| SCHEMBL12892667 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260022143-A1 | Cyclic Peptide Inhibitors of IL-23 | JANSSEN PHARMACEUTICA NV (BE) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260022143-A1 | Cyclic Peptide Inhibitors of IL-23 | IL23R, IL17A, IL36G | MAPK1 1334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.