Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SNCA | P37840 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1920769 | 0.89 | CYP3A4 (0.86) | CYP3A4TSHRHDAC6KMT2AMEN1 | |
| SCHEMBL8352093 | 0.85 | CYP3A4 (0.79) | CYP3A4TSHRHDAC6KMT2AMEN1 | |
| SCHEMBL30026816 | 0.85 | CYP3A4 (0.86) | CYP3A4TSHRHDAC6KMT2AMEN1 | |
| SCHEMBL1389429 | 0.85 | CYP3A4 (0.86) | CYP3A4TSHRHDAC6KMT2AMEN1 | |
| SCHEMBL1921475 | 0.83 | CYP3A4 (0.76) | CYP3A4TSHRHDAC6KMT2AMEN1 | |
| SCHEMBL219995 | 0.83 | CYP3A4 (1.00) | CYP3A4TSHRHDAC6KMT2AMEN1 | |
| SCHEMBL29678179 | 0.83 | CYP3A4 (1.00) | CYP3A4TSHRHDAC6KMT2AMEN1 | |
| SCHEMBL13302358 | 0.83 | CYP3A4 (0.82) | CYP3A4TSHRHDAC6KMT2AMEN1 | |
| SCHEMBL11475061 | 0.80 | CYP3A4 (0.70) | CYP3A4TSHRHDAC6KMT2AMEN1 | |
| SCHEMBL32665149 | 0.80 | CYP3A4 (0.53) | CYP3A4TSHRHDAC6KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | CYP3A4 4706/4885TSHR 2255/4885HDAC6 2191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.