Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | APP | P05067 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | S100B | P04271 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13302359 | 0.85 | CYP3A4 (0.64) | CYP3A4TSHRAPPALDH1A1MEN1 | |
| SCHEMBL1686500 | 0.85 | MEN1 (0.55) | CYP3A4TSHRALDH1A1MEN1MAPT | |
| SCHEMBL6346307 | 0.83 | ALDH1A1 (0.68) | CYP3A4TSHRALDH1A1MEN1MAPT | |
| SCHEMBL8352093 | 0.81 | CYP3A4 (0.79) | CYP3A4TSHRAPPALDH1A1MEN1 | |
| SCHEMBL25692156 | 0.80 | ALDH1A1 (0.46) | CYP3A4TSHRALDH1A1MEN1MAPT | |
| SCHEMBL32665451 | 0.80 | CYP3A4 (0.70) | CYP3A4TSHRAPPALDH1A1MEN1 | |
| SCHEMBL9703877 | 0.78 | ALDH1A1 (0.47) | CYP3A4TSHRAPPALDH1A1MEN1 | |
| SCHEMBL27878567 | 0.78 | SPHK2 (0.53) | CYP3A4TSHRAPPALDH1A1MEN1 | |
| SCHEMBL16621392 | 0.78 | AKR1C3 (0.53) | ALDH1A1MEN1MAPTKMT2AAR | |
| SCHEMBL1920769 | 0.76 | CYP3A4 (0.86) | CYP3A4TSHRAPPALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | CYP3A4 4706/4885TSHR 2255/4885APP 3638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.