SCHEMBL32665563

SCHEMBL32665563

O=C(O)/C=C\C(=O)NCCc1ccc(S(=O)(=O)F)cc1

nearest known ligand 0.69

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ TAAR1 Q96RJ0 6/20 0.66
▸ ALDH1A1 P00352 6/20 0.66
▸ MMP1 P03956 1/20 0.48
▸ POLB P06746 1/20 0.48
▸ MMP2 P08253 1/20 0.48
▸ MMP9 P14780 1/20 0.48
▸ RECQL P46063 1/20 0.48
▸ MAPT P10636 2/20 0.46
▸ MEN1 O00255 2/20 0.46
▸ KMT2A Q03164 2/20 0.46
▸ CACNA1B Q00975 1/20 0.46
▸ APBA1 Q02410 1/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.46
▸ LMNA P02545 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32665142 0.84 ALDH1A1 (0.64) TAAR1ALDH1A1MMP1POLBMMP2
SCHEMBL4017341 0.80 ALDH1A1 (1.00) TAAR1ALDH1A1MMP1POLBMMP2
SCHEMBL6891812 0.80 ALDH1A1 (1.00) TAAR1ALDH1A1MMP1POLBMMP2
SCHEMBL4017350 0.80 ALDH1A1 (1.00) TAAR1ALDH1A1MMP1POLBMMP2
SCHEMBL15494538 0.79 TAAR1 (0.73) TAAR1ALDH1A1MMP1POLBMMP2
SCHEMBL15431342 0.79 TAAR1 (0.73) TAAR1ALDH1A1MMP1POLBMMP2
SCHEMBL10844688 0.71 SMN1; SMN2 (0.54) TAAR1ALDH1A1MMP1POLBMMP2
SCHEMBL10843294 0.71 MAPT (0.65) ALDH1A1MAPTMEN1KMT2ACACNA1B
SCHEMBL10709429 0.71 SMN1; SMN2 (0.54) TAAR1ALDH1A1MMP1POLBMMP2
SCHEMBL10709043 0.71 MAPT (0.65) ALDH1A1MAPTMEN1KMT2ACACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260021192-A1 PROTEINS HAVING A COVALENT WARHEAD TOPAZ THERAPEUTICS INC (US) 2026-01-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260021192-A1 PROTEINS HAVING A COVALENT WARHEAD RIOX2, ORC3, DCLRE1A TAAR1 3910/4885ALDH1A1 3714/4885MMP1 3774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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