Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 2/20 | 0.60 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.58 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.55 |
| ▸ | GUSB | P08236 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.54 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32665502 | 0.88 | SMPD1 (0.55) | SMPD1SPHK2SPHK1MAOBNR4A2 | |
| SCHEMBL749687 | 0.87 | HDAC1 (0.60) | SPHK2SPHK1MAOBNR4A2MEN1 | |
| SCHEMBL24310073 | 0.86 | PTPN1 (0.55) | SMPD1SPHK2SPHK1MAOBNR4A2 | |
| SCHEMBL31506266 | 0.85 | CYP2D6 (0.58) | SPHK2SPHK1MAOBNR4A2CYP2D6 | |
| SCHEMBL67569 | 0.85 | CYP2D6 (0.58) | SPHK2SPHK1MAOBNR4A2CYP2D6 | |
| SCHEMBL7076430 | 0.83 | KMT2A (0.65) | SMPD1MAOBMEN1KMT2ANR1H4 | |
| SCHEMBL284764 | 0.83 | SMN1; SMN2 (0.55) | MEN1KMT2A | |
| SCHEMBL7281204 | 0.82 | CYP2D6 (0.52) | MAOBCYP2D6 | |
| SCHEMBL1754810 | 0.81 | POLB (0.58) | NPC1RAB9A | |
| SCHEMBL32665557 | 0.81 | SPHK2 (0.83) | SMPD1SPHK2SPHK1MAOBNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | SMPD1 4331/4885SPHK2 4730/4885SPHK1 4786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.