Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NQO2 | P16083 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.48 |
| ▸ | TP53BP1 | Q12888 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | ACACA | Q13085 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL264483 | 0.94 | SMN1; SMN2 (0.50) | SMN1; SMN2NQO2L3MBTL1KMT2AGAA | |
| SCHEMBL5663889 | 0.94 | SMN1; SMN2 (0.50) | SMN1; SMN2NQO2L3MBTL1KMT2AGAA | |
| SCHEMBL16152246 | 0.94 | SMN1; SMN2 (0.60) | SMN1; SMN2NQO2L3MBTL1KMT2AGAA | |
| SCHEMBL265731 | 0.93 | SMN1; SMN2 (0.49) | SMN1; SMN2NQO2L3MBTL1KMT2AGAA | |
| SCHEMBL284884 | 0.93 | SMN1; SMN2 (0.59) | SMN1; SMN2TP53BP1LMNA | |
| SCHEMBL14679371 | 0.91 | NPC1 (0.57) | SMN1; SMN2KMT2AGAAALDH1A1MEN1 | |
| SCHEMBL10123873 | 0.90 | ALDH1A1 (0.47) | SMN1; SMN2NQO2L3MBTL1KMT2AHSD17B10 | |
| SCHEMBL5663105 | 0.90 | TP53BP1 (0.62) | SMN1; SMN2NQO2L3MBTL1KMT2AMALT1 | |
| SCHEMBL1754810 | 0.89 | POLB (0.58) | SMN1; SMN2GAAMALT1POLBBCHE | |
| SCHEMBL16151786 | 0.89 | SMN1; SMN2 (0.71) | SMN1; SMN2L3MBTL1KMT2AGAATP53BP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580749-B2 | Dyes and labeled molecules | BIOTIUM, INC. (US) | 2017-02-28 | — | — | US | disclosed |
| CN-102942566-B | Dimerization and trimerization nucleic acid dye and relevant system and method | BIOTIUM INC. (US) | 2016-04-20 | — | — | CN | disclosed |
| CN-101142326-B | Dimeric and trimeric nucleic acid dyes and related systems and methods | BIOTIUM, INC. (US) | 2015-09-30 | — | — | CN | disclosed |
| US-9102835-B2 | Methods of using dyes in association with nucleic acid staining or detection and associated technology | BIOTIUM, INC. (US) | 2015-08-11 | — | — | US | disclosed |
| US-8753814-B2 | Methods of using dyes in association with nucleic acid staining or detection and associated technology | BIOTIUM, INC. (US) | 2014-06-17 | — | — | US | disclosed |
| US-20140106349-A1 | Dyes and Labeled Molecules | ALLELOGIC BIOSCIENCES CORPORATION (US) | 2014-04-17 | — | — | US | disclosed |
| US-20140073058-A1 | Methods of Using Dyes in Association with Nucleic Acid Staining or Detection and Associated Technology | BIOTIUM, INC. (US) | 2014-03-13 | — | — | US | disclosed |
| US-8530195-B2 | Dyes and labeled molecules | BIOTIUM, INC. (US) | 2013-09-10 | — | — | US | disclosed |
| US-20130167309-A1 | METHODS OF USING DYES IN ASSOCIATION WITH NUCLEIC ACID STAINING OR DETECTION AND ASSOCIATED TECHNOLOGY | BIOTIUM, INC. (US) | 2013-07-04 | — | — | US | disclosed |
| EP-2428586-B1 | Dimeric nucleic acid dyes, and associated systems and methods | BIOTIUM INC (US) | 2013-05-08 | — | — | EP | disclosed |
| US-20100317016-A1 | DYES AND LABELED MOLECULES | BIOTIUM, INC. (US) | 2010-12-16 | — | — | US | disclosed |
| US-7803943-B2 | Methods of using dyes in association with nucleic acid staining or detection and associated technology | BIOTIUM, INC. (US) | 2010-09-28 | — | — | US | disclosed |
| US-7776567-B2 | Dimeric and trimeric nucleic acid dyes, and associated systems and methods | BIOTIUM, INC. (US) | 2010-08-17 | — | — | US | disclosed |
| US-20100009454-A1 | METHODS OF USING DYES IN ASSOCIATION WITH NUCLEIC ACID STAINING OR DETECTION AND ASSOCIATED TECHNOLOGY | BIOTIUM, INC. | 2010-01-14 | — | — | US | disclosed |
| US-7601498-B2 | Methods of using dyes in association with nucleic acid staining or detection and associated technology | BIOTIUM, INC. (US) | 2009-10-13 | — | — | US | disclosed |
| EP-1863933-A4 | DIMERIC AND TRIMERIC NUCLEIC ACID DYES, AND ASSOCIATED SYSTEMS AND METHODS | BIOTIUM INC (US) | 2009-04-08 | — | — | EP | disclosed |
| EP-1863933-A2 | DIMERIC AND TRIMERIC NUCLEIC ACID DYES, AND ASSOCIATED SYSTEMS AND METHODS | Biotium Inc. (US) | 2007-12-12 | — | — | EP | disclosed |
| US-20060211028-A1 | Dimeric and trimeric nucleic acid dyes, and associated systems and methods | ALLELOGIC BIOSCIENCES CORPORATION | 2006-09-21 | — | — | US | disclosed |
| US-20060211029-A1 | Methods of using dyes in association with nucleic acid staining or detection and associated technology | BIOTIUM, INC. | 2006-09-21 | — | — | US | disclosed |
| WO-2006099605-A2 | DIMERIC AND TRIMERIC NUCLEIC ACID DYES, AND ASSOCIATED SYSTEMS AND METHODS | BIOTIUM, INC. (US) | 2006-09-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317016-A1 | DYES AND LABELED MOLECULES | DNA2, POLL, POLRMT | SMN1; SMN2 3673/4885NQO2 1703/4885L3MBTL1 580/4885 |
| US-20060211028-A1 | Dimeric and trimeric nucleic acid dyes, and associated systems and methods | DNA2, POLRMT, POLL | SMN1; SMN2 2672/4885NQO2 2307/4885L3MBTL1 1030/4885 |
| US-20060211029-A1 | Methods of using dyes in association with nucleic acid staining or detection and associated technology | HNRNPLL, HNRNPL, HNRNPH3 | SMN1; SMN2 2523/4885NQO2 2280/4885L3MBTL1 999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.