Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.60 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.60 |
| ▸ | NAAA | Q02083 | 1/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | MGLL | Q99685 | 5/20 | 0.56 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.53 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22688327 | 1.00 | ALDH1A1 (0.72) | ALDH1A1PDE3BPDE3ANAAANR4A2 | |
| SCHEMBL24304100 | 0.86 | ALDH1A1 (0.67) | ALDH1A1NAAANR4A2MAOBMGLL | |
| SCHEMBL11085975 | 0.84 | ALDH1A1 (0.74) | ALDH1A1NAAANR4A2MAOBMGLL | |
| SCHEMBL32665570 | 0.82 | ALDH1A1 (0.61) | ALDH1A1PDE3BPDE3ANAAANR4A2 | |
| SCHEMBL32665324 | 0.79 | ALDH1A1 (0.58) | ALDH1A1PDE3BPDE3ANAAANR4A2 | |
| SCHEMBL3354512 | 0.79 | ALDH1A1 (0.57) | ALDH1A1PDE3BPDE3ANAAANR4A2 | |
| SCHEMBL22864871 | 0.79 | ALDH1A1 (0.67) | ALDH1A1NAAANR4A2MAOBMGLL | |
| SCHEMBL22864867 | 0.79 | ALDH1A1 (0.67) | ALDH1A1NAAANR4A2MAOBMGLL | |
| SCHEMBL4321888 | 0.78 | MEN1 (0.78) | ALDH1A1MGLLRAB9ASMN1; SMN2LMNA | |
| SCHEMBL13097312 | 0.78 | NPC1 (0.58) | NR4A2MAOBNPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | ALDH1A1 3714/4885PDE3B 4874/4885PDE3A 4881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.