SCHEMBL32665693

SCHEMBL32665693

c1ccc(-c2nc(-c3nc4ccccc4[nH]3)cs2)cc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.78
ALDH1A1 P00352 6/20 0.78
TP53 P04637 5/20 0.78
HPGD P15428 5/20 0.78
HSD17B10 Q99714 4/20 0.78
ALOX15 P16050 3/20 0.78
CYP3A4 P08684 2/20 0.78
TDP1 Q9NUW8 2/20 0.78
KMT2A Q03164 2/20 0.78
MEN1 O00255 1/20 0.78
MAPT P10636 1/20 0.78
MAPK1 P28482 1/20 0.78
BRCA1 P38398 1/20 0.78
RAB9A P51151 9/20 0.66
NPC1 O15118 8/20 0.66
SMN1; SMN2 Q16637 8/20 0.66
FKBP1A P62942 2/20 0.66
GAA P10253 1/20 0.60
METAP2 P50579 3/20 0.54
TSHR P16473 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32665696 0.98 KDM4E (0.76) KDM4EALDH1A1TP53HPGDHSD17B10
SCHEMBL32665695 0.98 KDM4E (0.76) KDM4EALDH1A1TP53HPGDHSD17B10
SCHEMBL7965438 0.88 KDM4E (1.00) KDM4EALDH1A1TP53HPGDHSD17B10
SCHEMBL8343381 0.85 KDM4E (0.94) KDM4EALDH1A1TP53HPGDHSD17B10
SCHEMBL3140719 0.80 RAB9A (1.00) KDM4EALDH1A1TP53HPGDHSD17B10
SCHEMBL9457146 0.78 NPC1 (0.69) KDM4EALDH1A1TP53HPGDHSD17B10
SCHEMBL11858858 0.78 NPC1 (0.69) KDM4EALDH1A1TP53HPGDHSD17B10
SCHEMBL28427886 0.78 NPC1 (0.69) KDM4EALDH1A1TP53HPGDHSD17B10
SCHEMBL7441069 0.78 NPC1 (0.69) KDM4EALDH1A1TP53HPGDHSD17B10
SCHEMBL19095093 0.78 NPC1 (0.57) KDM4EALDH1A1TP53HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121378294-A Benzimidazolyl phenyl thiazole copper complex and synthetic method and application thereof 哈工大郑州研究院 2026-01-23 CN disclosed