Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.49 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21822394 | 1.00 | F10 (0.49) | F10NOD2NOD1KMT2AMEN1 | |
| SCHEMBL25016919 | 0.91 | CCR2 (0.39) | F10KDM4ETDP1ALDH1A1 | |
| SCHEMBL25015783 | 0.89 | F10 (0.44) | F10NOD2NOD1KMT2AMEN1 | |
| SCHEMBL25016935 | 0.87 | F10 (0.43) | F10NOD2NOD1KMT2AMEN1 | |
| SCHEMBL25017612 | 0.86 | F10 (0.41) | F10NOD2NOD1KMT2AMEN1 | |
| SCHEMBL25016299 | 0.85 | F10 (0.41) | F10NOD2NOD1KMT2AMEN1 | |
| SCHEMBL25016547 | 0.84 | F10 (0.39) | F10NOD2NOD1KMT2AMEN1 | |
| SCHEMBL25015781 | 0.83 | F10 (0.67) | F10NOD2NOD1KMT2AMEN1 | |
| SCHEMBL25016231 | 0.82 | F10 (0.44) | F10F2 | |
| SCHEMBL25017211 | 0.80 | RHEB (0.40) | F10F2GAAPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3860636-B1 | MATRIPTASE 2 INHIBITORS AND USES THEREOF | DISC MEDICINE INC (US) | 2026-01-28 | — | — | EP | disclosed |