Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.38 |
| ▸ | IDH2 | P48735 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 2/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3234022 | 0.98 | SYK (0.42) | SYKADORA1IDH2VCPPLK1 | |
| SCHEMBL3264006 | 0.96 | SYK (0.42) | SYKADORA1IDH2VCPPLK1 | |
| SCHEMBL3265292 | 0.94 | SYK (0.43) | SYKADORA1IDH2VCPPLK1 | |
| SCHEMBL3263101 | 0.91 | SYK (0.41) | SYKADORA1IDH2VCPPLK1 | |
| SCHEMBL3419382 | 0.90 | SYK (0.43) | SYKADORA1IDH2VCPPLK1 | |
| SCHEMBL3233798 | 0.90 | VCP (0.43) | SYKADORA1IDH2VCPPLK1 | |
| SCHEMBL3415621 | 0.90 | SYK (0.40) | SYKADORA1IDH2VCPPLK1 | |
| SCHEMBL3236168 | 0.90 | AKT1 (0.40) | SYKADORA1IDH2VCPPLK1 | |
| SCHEMBL3228688 | 0.90 | SYK (0.40) | SYKADORA1IDH2VCPPLK1 | |
| SCHEMBL3224000 | 0.89 | SYK (0.44) | SYKADORA1VCPAKR1C1PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010028179-A1 | HETEROCYCLIC COMPOUNDS AS GATA MODULATORS | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-03-11 | — | — | WO | claimed |