Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 8/20 | 0.61 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 2/20 | 0.35 |
| ▸ | MC5R | P33032 | 2/20 | 0.35 |
| ▸ | MC3R | P41968 | 2/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3266740 | 1.00 | GHSR (0.61) | GHSRMMP9MMP8MC4RMC5R | |
| SCHEMBL18472634 | 0.90 | GHSR (0.65) | GHSRMMP9MMP8MC4RMC5R | |
| SCHEMBL3266602 | 0.90 | GHSR (0.59) | GHSRMMP9MMP8MC4RMC5R | |
| SCHEMBL3266594 | 0.90 | GHSR (0.59) | GHSRMMP9MMP8MC4RMC5R | |
| SCHEMBL6320638 | 0.89 | GHSR (0.66) | GHSRMMP9MMP8MC4RMC5R | |
| SCHEMBL6320645 | 0.89 | GHSR (0.66) | GHSRMMP9MMP8MC4RMC5R | |
| SCHEMBL6325612 | 0.89 | GHSR (0.66) | GHSRMMP9MMP8MC4RMC5R | |
| SCHEMBL3267114 | 0.89 | GHSR (0.60) | GHSRMMP9MMP8MC4RMC5R | |
| SCHEMBL3267122 | 0.89 | GHSR (0.60) | GHSRMMP9MMP8MC4RMC5R | |
| SCHEMBL3266932 | 0.89 | GHSR (0.62) | GHSRMMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047709-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-11-03 | — | — | EP | claimed |
| US-6083908-A | TREATING MEDICAL DISORDERS RESULTING FROM DEFICIENCY IN GROWTH HORMONE | NOVO NORDISK A/S (DK) | 2000-07-04 | — | — | US | claimed |
| EP-1506969-B1 | Compounds with growth hormone releasing properties | HELSINN THERAPEUTICS US INC (US) | 2010-06-09 | — | — | EP | disclosed |
| EP-1506969-A1 | Compounds with growth hormone releasing properties | NOVO NORDISK A/S (DK) | 2005-02-16 | — | — | EP | disclosed |
| EP-1047709-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-11-03 | — | — | EP | disclosed |
| US-6083908-A | TREATING MEDICAL DISORDERS RESULTING FROM DEFICIENCY IN GROWTH HORMONE | NOVO NORDISK A/S (DK) | 2000-07-04 | — | — | US | disclosed |