Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21525564 | 1.00 | HTT (0.59) | HTTALDH1A1LMNAXBP1MAPT | |
| SCHEMBL21525512 | 0.85 | HTT (0.59) | HTTALDH1A1LMNAXBP1MAPT | |
| SCHEMBL32668827 | 0.85 | HTT (0.59) | HTTALDH1A1LMNAXBP1MAPT | |
| SCHEMBL17869860 | 0.81 | HTT (0.67) | HTTALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL4697615 | 0.81 | HTT (0.53) | HTTALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL3755962 | 0.80 | HTT (0.65) | HTTALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL3761515 | 0.79 | HTT (0.64) | HTTALDH1A1LMNAXBP1MAPT | |
| SCHEMBL17869787 | 0.76 | HTT (0.53) | HTTALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL2077064 | 0.76 | MAPT (0.59) | HTTALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL17869621 | 0.75 | XDH (0.60) | HTTALDH1A1LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3623372-B1 | PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS | VALO HEALTH INC (US) | 2026-02-04 | — | — | EP | disclosed |