Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | PARP1 | P09874 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PDE9A | O76083 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17869787 | 0.85 | HTT (0.53) | HTTALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL30155205 | 0.83 | HTT (0.54) | XDHHTTALDH1A1MAPTMEN1 | |
| SCHEMBL17869860 | 0.82 | HTT (0.67) | XDHHTTALDH1A1MAPTMEN1 | |
| SCHEMBL4697615 | 0.82 | HTT (0.53) | XDHHTTALDH1A1MAPTMEN1 | |
| SCHEMBL2077064 | 0.81 | MAPT (0.59) | HTTALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL32668606 | 0.81 | MAPT (0.56) | HTTALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL17869789 | 0.80 | HTT (0.51) | XDHHTTALDH1A1MAPTMEN1 | |
| SCHEMBL32668800 | 0.80 | HTT (0.51) | XDHHTTPARP1ALDH1A1MAPT | |
| SCHEMBL17869621 | 0.78 | XDH (0.60) | XDHHTTALDH1A1MAPTMEN1 | |
| SCHEMBL17869553 | 0.78 | XDH (0.62) | XDHHTTALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3623372-B1 | PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS | VALO HEALTH INC (US) | 2026-02-04 | — | — | EP | disclosed |