SCHEMBL32668974

SCHEMBL32668974

CCCNC(=O)C1=CC(=Nc2ccc(N(CC)CC)cc2OCC)c2ccccc2C1=O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 2/20 0.35
PTPRC P08575 2/20 0.34
CDC25B P30305 1/20 0.34
KDM4E B2RXH2 6/20 0.34
MAPT P10636 5/20 0.34
ALDH1A1 P00352 5/20 0.34
KMT2A Q03164 4/20 0.34
MEN1 O00255 3/20 0.34
HTT P42858 3/20 0.34
HPGD P15428 3/20 0.34
MAPK1 P28482 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
LMNA P02545 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
THRB P10828 1/20 0.34
MCL1 Q07820 1/20 0.34
ATM Q13315 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13725181 0.81 KMT2A (0.37) MAPTALDH1A1KMT2AMEN1HTT
SCHEMBL13763576 0.79 ALDH1A1 (0.36) KDM4EMAPTALDH1A1KMT2AMEN1
SCHEMBL14442097 0.79 ALDH1A1 (0.36) KDM4EMAPTALDH1A1KMT2AMEN1
SCHEMBL13839260 0.77 ALDH1A1 (0.36) KDM4EMAPTALDH1A1KMT2AMEN1
SCHEMBL14484580 0.76 RPS6KA2 (0.40) HCRTR1KDM4EMAPTALDH1A1KMT2A
SCHEMBL12764843 0.76 RPS6KA2 (0.40) HCRTR1KDM4EMAPTALDH1A1KMT2A
SCHEMBL14594205 0.72 RPS6KA2 (0.39) HCRTR1KDM4EMAPTALDH1A1KMT2A
SCHEMBL13840586 0.72 ALDH1A1 (0.36) MAPTALDH1A1KMT2AMEN1HTT
SCHEMBL10820047 0.70 MEN1 (0.45) KDM4EMAPTALDH1A1KMT2AMEN1
SCHEMBL12764857 0.70 MEN1 (0.45) KDM4EMAPTALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4686757-A1 INHIBITORS OF EXPRESSION AND/OR FUNCTION e-therapeutics PLC (GB) 2026-02-04 EP disclosed