SCHEMBL32668997

SCHEMBL32668997

CC(=O)OCC(=O)C1(OC(C)=O)CCC2C3CC(F)C4=CC(=O)C=CC4(C)C34OC4CC21C

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 10/20 0.63
LMNA P02545 7/20 0.63
NPSR1 Q6W5P4 2/20 0.63
PGR P06401 7/20 0.52
AR P10275 6/20 0.52
CYP3A4 P08684 6/20 0.52
NR3C1 P04150 4/20 0.52
ALDH1A1 P00352 3/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
CYP1A2 P05177 1/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
KDM4E B2RXH2 2/20 0.44
ABCB11 O95342 1/20 0.42
MAPT P10636 2/20 0.42
CNR1 P21554 1/20 0.42
KCNH2 Q12809 1/20 0.42
USP2 O75604 1/20 0.42
POLB P06746 1/20 0.42
F2 P00734 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11362338 1.00 HIF1A (0.63) HIF1ALMNANPSR1PGRAR
SCHEMBL5708002 1.00 HIF1A (0.63) HIF1ALMNANPSR1PGRAR
SCHEMBL10937267 1.00 HIF1A (0.63) HIF1ALMNANPSR1PGRAR
SCHEMBL11321400 0.94 HIF1A (0.66) HIF1ALMNANPSR1PGRAR
SCHEMBL11321398 0.94 HIF1A (0.66) HIF1ALMNANPSR1PGRAR
SCHEMBL11325169 0.92 HIF1A (0.75) HIF1ALMNANPSR1PGRAR
SCHEMBL11325170 0.92 HIF1A (0.75) HIF1ALMNANPSR1PGRAR
SCHEMBL11322896 0.90 HIF1A (0.52) HIF1ALMNANPSR1PGRAR
SCHEMBL11322898 0.90 HIF1A (0.52) HIF1ALMNANPSR1PGRAR
SCHEMBL11310944 0.89 HIF1A (0.56) HIF1ALMNANPSR1PGRAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4686757-A1 INHIBITORS OF EXPRESSION AND/OR FUNCTION e-therapeutics PLC (GB) 2026-02-04 EP disclosed