Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 10/20 | 0.63 |
| ▸ | LMNA | P02545 | 7/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.63 |
| ▸ | PGR | P06401 | 7/20 | 0.52 |
| ▸ | AR | P10275 | 6/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11362338 | 1.00 | HIF1A (0.63) | HIF1ALMNANPSR1PGRAR | |
| SCHEMBL10937267 | 1.00 | HIF1A (0.63) | HIF1ALMNANPSR1PGRAR | |
| SCHEMBL32668997 | 1.00 | HIF1A (0.63) | HIF1ALMNANPSR1PGRAR | |
| SCHEMBL11321400 | 0.94 | HIF1A (0.66) | HIF1ALMNANPSR1PGRAR | |
| SCHEMBL11321398 | 0.94 | HIF1A (0.66) | HIF1ALMNANPSR1PGRAR | |
| SCHEMBL11325169 | 0.92 | HIF1A (0.75) | HIF1ALMNANPSR1PGRAR | |
| SCHEMBL11325170 | 0.92 | HIF1A (0.75) | HIF1ALMNANPSR1PGRAR | |
| SCHEMBL11322896 | 0.90 | HIF1A (0.52) | HIF1ALMNANPSR1PGRAR | |
| SCHEMBL11322898 | 0.90 | HIF1A (0.52) | HIF1ALMNANPSR1PGRAR | |
| SCHEMBL11310944 | 0.89 | HIF1A (0.56) | HIF1ALMNANPSR1PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1422235-B1 | STEREOSELECTIVE METHOD OF PRODUCING 6ALPHA-FLUOROPREGNANES AND INTERMEDIARIES | RAGACTIVES SL (ES) | 2006-10-04 | — | — | EP | disclosed |
| US-20040181055-A1 | Stereoselective process for the production of 6alpha-fluorpregnanes and intermediates | RAGACTIVES, S.L. | 2004-09-16 | — | — | US | disclosed |
| EP-1422235-A1 | STEREOSELECTIVE METHOD OF PRODUCING 6ALPHA-FLUOROPREGNANES AND INTERMEDIARIES | Ragactives, S.L. (ES) | 2004-05-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040181055-A1 | Stereoselective process for the production of 6alpha-fluorpregnanes and intermediates | NR5A1, SRD5A2, SRD5A1 | HIF1A 1830/4885LMNA 2893/4885NPSR1 161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.