Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21804721 | 0.84 | HSP90AB1 (0.51) | ALDH1A1GAAGFERHSP90AB1CYP4F2 | |
| SCHEMBL30393854 | 0.82 | HSP90AB1 (0.56) | ALDH1A1GAAGFERHSP90AB1CYP4F2 | |
| SCHEMBL5156427 | 0.78 | ALDH1A1 (0.64) | ALDH1A1GAAGFERHSP90AB1CYP4F2 | |
| SCHEMBL29518485 | 0.78 | ALDH1A1 (0.64) | ALDH1A1GAAGFERHSP90AB1CYP4F2 | |
| SCHEMBL5093783 | 0.76 | ALDH1A1 (0.67) | ALDH1A1GAAGFERHSP90AB1CYP4F2 | |
| SCHEMBL2786552 | 0.76 | HSP90AB1 (0.63) | ALDH1A1GAAGFERHSP90AB1CYP4F2 | |
| SCHEMBL12678868 | 0.76 | HSP90AB1 (0.58) | ALDH1A1GAAGFERHSP90AB1CYP4F2 | |
| SCHEMBL31075998 | 0.76 | HSP90AB1 (0.54) | ALDH1A1GAAGFERHSP90AB1CYP4F2 | |
| SCHEMBL31075734 | 0.75 | HSP90AB1 (0.49) | ALDH1A1GAAGFERHSP90AB1CYP4F2 | |
| SCHEMBL23380842 | 0.75 | HSP90AB1 (0.56) | ALDH1A1GAAGFERHSP90AB1CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260034126-A1 | KRAS INHIBITORS | INCYTE CORP (US) | 2026-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260034126-A1 | KRAS INHIBITORS | KRAS, NRAS, HRAS | ALDH1A1 3023/4885GAA 4419/4885GFER 3101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.