⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3277201 | 0.98 | LCK (0.48) | — | |
| SCHEMBL8985634 | 0.98 | LCK (0.48) | — | |
| SCHEMBL8985585 | 0.98 | LCK (0.48) | — | |
| SCHEMBL3271769 | 0.98 | LCK (0.48) | — | |
| SCHEMBL738319 | 0.98 | LCK (0.48) | — | |
| SCHEMBL1314019 | 0.98 | LCK (0.48) | — | |
| SCHEMBL4725182 | 0.92 | — | — | |
| SCHEMBL28813034 | 0.90 | — | — | |
| SCHEMBL28988982 | 0.90 | — | — | |
| SCHEMBL922060 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114053394-B | Application of novel compound in preparation of medicines for preventing and/or treating coronavirus infection | 广州朗圣药业有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-114053392-B | Application of novel compound in preparation of medicine for preventing and/or treating HPV infection | 广州朗圣药业有限公司 | 2024-06-21 | — | — | CN | disclosed |
| EP-4281072-A1 | FERROPORTIN-INHIBITORS FOR THE USE IN THE TREATMENT OF MYELODYSPLASTIC SYNDROMES (MDS) | VIFOR (INTERNATIONAL) AG (CH) | 2023-11-29 | — | — | EP | disclosed |
| US-20220273634-A1 | Ferroportin-Inhibitors For The Use In The Treatment Of Transfusion-Dependent Beta-Thalassemia (TDT) | VIFOR (INTERNATIONAL) AG (CH) | 2022-09-01 | — | — | US | disclosed |
| EP-3999059-A1 | FERROPORTIN-INHIBITORS FOR THE USE IN THE TREATMENT OF TRANSFUSION-DEPENDENT BETA-THALASSEMIA (TDT) | VIFOR (INTERNATIONAL) AG (CH) | 2022-05-25 | — | — | EP | disclosed |
| EP-3999060-A1 | FERROPORTIN-INHIBITORS FOR THE USE IN THE PREVENTION AND TREATMENT OF KIDNEY INJURIES | VIFOR (INTERNATIONAL) AG (CH) | 2022-05-25 | — | — | EP | disclosed |
| CN-113135940-B | Benzothiazole pyrimidine ring compound and preparation method and application thereof | 成都大学 | 2022-05-03 | — | — | CN | disclosed |
| CN-114053394-A | Application of novel compound in preparation of medicine for preventing and/or treating coronavirus infection | 广州朗圣药业有限公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-114053392-A | Application of novel compound in preparation of medicine for preventing and/or treating HPV infection | 广州朗圣药业有限公司 | 2022-02-18 | — | — | CN | disclosed |
| US-11129820-B2 | Ferroportin-inhibitor salts | VIFOR (INTERNATIONAL) AG (CH) | 2021-09-28 | — | — | US | disclosed |
| US-6117867-A | IN MEDICINE AND VETERINARY MEDICINE | PROCTER & GAMBLE COMPANY (US) | 2000-09-12 | — | — | US | disclosed |
| EP-0877026-A1 | SUBSTITUTED 6-R-1,3,4-THIADIAZINE-2-AMINES, THE USE THEREOF AS ANAESTHETISING, CARDIOVASCULAR AND HYPOMETABOLIC AGENTS, AND A PHARMACEUTICAL COMPOSITION CONTAINING THEM | THE PROCTER & GAMBLE COMPANY (US) | 1998-11-11 | — | — | EP | disclosed |
| US-4772717-A | Novel process for the preparation of biotin | PFIZER INC. (US) | 1988-09-20 | — | — | US | disclosed |
| EP-0094776-B1 | NOVEL PROCESS FOR THE PREPARATION OF BIOTIN | PFIZER INC. (US) | 1988-06-22 | — | — | EP | disclosed |
| US-4732988-A | Bicyclic precursors for the preparation of biotin | PFIZER INC. (US) | 1988-03-22 | — | — | US | disclosed |
| US-4694087-A | Imidazolidinone precursors for the preparation of biotin | PFIZER INC. (US) | 1987-09-15 | — | — | US | disclosed |
| US-4631345-A | Thiazole precursors for the preparation of biotin | PFIZER INC. (US) | 1986-12-23 | — | — | US | disclosed |
| US-4581459-A | Process for the preparation of biotin | PFIZER INC. (US) | 1986-04-08 | — | — | US | disclosed |
| US-4468516-A | Process for the preparation of biotin | PFIZER INC. (US) | 1984-08-28 | — | — | US | disclosed |
| EP-0094776-A2 | Novel process for the preparation of biotin | PFIZER INC. (US) | 1983-11-23 | — | — | EP | disclosed |