⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8295411 | 1.00 | — | — | |
| SCHEMBL4725182 | 0.83 | — | — | |
| SCHEMBL3266925 | 0.81 | — | — | |
| SCHEMBL28988982 | 0.81 | — | — | |
| SCHEMBL28813034 | 0.81 | — | — | |
| SCHEMBL27824525 | 0.81 | — | — | |
| SCHEMBL8985634 | 0.79 | LCK (0.48) | — | |
| SCHEMBL1314019 | 0.79 | LCK (0.48) | — | |
| SCHEMBL8985585 | 0.79 | LCK (0.48) | — | |
| SCHEMBL3271769 | 0.79 | LCK (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114053394-B | Application of novel compound in preparation of medicines for preventing and/or treating coronavirus infection | 广州朗圣药业有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-114053392-B | Application of novel compound in preparation of medicine for preventing and/or treating HPV infection | 广州朗圣药业有限公司 | 2024-06-21 | — | — | CN | disclosed |
| US-20240002348-A1 | QUINOLONE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) | 2024-01-04 | — | — | US | disclosed |
| EP-4288048-A1 | OXA-IBOGAINE INSPIRED ANALOGUES FOR TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | The Trustees Of Columbia University In The City Of New York (US) | 2023-12-13 | — | — | EP | disclosed |
| US-20230382919-A1 | OXA- IBOGAINE INSPIRED ANALOGUES FOR TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-11-30 | — | — | US | disclosed |
| CN-117120050-A | Oxa-ibogine inspired analogues for the treatment of neurological and psychiatric disorders | 纽约哥伦比亚大学董事会 | 2023-11-24 | — | — | CN | disclosed |
| EP-4204410-A1 | QUINOLONE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | Council of Scientific & Industrial Research, an Indian registered body incorporated under the Registration of Societies Act (Act XXI of 1860) (IN) | 2023-07-05 | — | — | EP | disclosed |
| WO-2022170268-A1 | OXA-IBOGAINE INSPIRED ANALOGUES FOR TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-08-11 | — | — | WO | disclosed |
| CN-113135940-B | Benzothiazole pyrimidine ring compound and preparation method and application thereof | 成都大学 | 2022-05-03 | — | — | CN | disclosed |
| CN-113135940-A | Benzothiazole pyrimidine ring compound and preparation method and application thereof | 成都大学 | 2021-07-20 | — | — | CN | disclosed |
| EP-1311488-A1 | SUBSTITUTED IMIDAZOLES AS TAFIA INHIBITORS | Pfizer Limited (GB) | 2003-05-21 | — | — | EP | disclosed |
| US-20020147229-A1 | Pharmaceuticals | PFIZER INC. | 2002-10-10 | — | — | US | disclosed |
| WO-2002014285-A1 | SUBSTITUTED IMIDAZOLES AS TAFIA INHIBITORS | PFIZER LIMITED (GB) | 2002-02-21 | — | — | WO | disclosed |
| CN-1298389-A | Cyclic amine compound | SANKYO CO (JP) | 2001-06-06 | — | — | CN | disclosed |
| US-5733882-A | Retroviral protease inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 1998-03-31 | — | — | US | disclosed |
| EP-0602069-A4 | RETROVIRAL PROTEASE INHIBITORS. | SMITHKLINE BEECHAM CORP (US) | 1995-05-03 | — | — | EP | disclosed |
| EP-0603309-A1 | PEPTIDE ISOTERS CONTAINING A HETEROCYCLE AS H.I.V. INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-06-29 | — | — | EP | disclosed |
| EP-0602069-A1 | RETROVIRAL PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-06-22 | — | — | EP | disclosed |
| WO-1993005026-A1 | PEPTIDE ISOTERS CONTAINING A HETEROCYCLE AS H.I.V. INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-03-18 | — | — | WO | disclosed |
| WO-1993002057-A1 | RETROVIRAL PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-02-04 | — | — | WO | disclosed |