SCHEMBL32670314

SCHEMBL32670314

CCOC(=O)Cc1coc2cc(Br)c(F)cc12

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 4/20 0.46
▸ KMT2A Q03164 4/20 0.46
▸ POLB P06746 3/20 0.46
▸ GAA P10253 1/20 0.46
▸ ALOX15 P16050 2/20 0.45
▸ TSHR P16473 5/20 0.43
▸ MAPT P10636 5/20 0.40
▸ SMN1; SMN2 Q16637 4/20 0.40
▸ L3MBTL1 Q9Y468 2/20 0.40
▸ TDP1 Q9NUW8 1/20 0.40
▸ LMNA P02545 2/20 0.39
▸ ADRB2 P07550 1/20 0.39
▸ HSD17B10 Q99714 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.37
▸ HPGD P15428 1/20 0.37
▸ PAX8 Q06710 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31426171 0.95 MEN1 (0.46) MEN1KMT2APOLBGAAALOX15
SCHEMBL32670302 0.87 ALOX15 (0.54) MEN1KMT2APOLBGAAALOX15
SCHEMBL19627162 0.84 ALOX15 (0.54) MEN1KMT2APOLBGAAALOX15
SCHEMBL23117392 0.84 MAPT (0.47) MEN1KMT2APOLBGAAALOX15
SCHEMBL23116734 0.83 MEN1 (0.49) MEN1KMT2APOLBGAAALOX15
SCHEMBL17785120 0.81 TSHR (0.47) MEN1KMT2APOLBGAAALOX15
SCHEMBL19627184 0.81 ALOX15 (0.68) MEN1KMT2APOLBGAAALOX15
SCHEMBL23117269 0.79 POLB (0.56) MEN1KMT2APOLBGAAALOX15
SCHEMBL23116701 0.79 TSHR (0.58) MEN1KMT2APOLBGAAALOX15
SCHEMBL8175604 0.79 MEN1 (0.47) MEN1KMT2APOLBGAAALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035361-A1 COMPOUNDS FOR MODULATING HUR (ELAVL1) SHANGHAI DEGRON BIOMEDICAL TECH CO LTD (CN) 2026-02-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035361-A1 COMPOUNDS FOR MODULATING HUR (ELAVL1) ELAVL1, ELAVL3, HNRNPL MEN1 1990/4885KMT2A 3940/4885POLB 3895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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