Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 5/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48371 | 0.83 | PIK3CD (0.67) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL3602972 | 0.79 | PIK3CD (0.50) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL27930246 | 0.78 | XDH (0.45) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL3949427 | 0.76 | DYRK1A (0.70) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL3953825 | 0.76 | ACP1 (0.60) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL30493298 | 0.76 | DYRK1A (0.70) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL5049032 | 0.76 | MEN1 (0.64) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL5048932 | 0.74 | MAPT (0.49) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL1532248 | 0.73 | KMT2A (0.59) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL26087243 | 0.73 | LCK (0.60) | MAPTMEN1KMT2ALCKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260034105-A1 | Generative AI-Assisted Identification of Novel PI3K-alpha Inhibitors | THE FIRST AFFILIATED HOSPITAL OF XI'AN JIAOTONG UNIVERSITY (CN) | 2026-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260034105-A1 | Generative AI-Assisted Identification of Novel PI3K-alpha Inhibitors | PIK3R1, PIK3R4, PIK3R2 | MAPT 4207/4885MEN1 4252/4885KMT2A 2776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.