Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 8/20 | 0.58 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3267086 | 1.00 | GHSR (0.58) | GHSRCTSBCTSSCTSKPTPN1 | |
| SCHEMBL3266770 | 0.93 | GHSR (0.60) | GHSRCTSBCTSSCTSKPTPN1 | |
| SCHEMBL3266765 | 0.93 | GHSR (0.60) | GHSRCTSBCTSSCTSKPTPN1 | |
| SCHEMBL3266457 | 0.91 | GHSR (0.59) | GHSRCTSBCTSSCTSKPTPN1 | |
| SCHEMBL3266455 | 0.91 | GHSR (0.59) | GHSRCTSBCTSSCTSKPTPN1 | |
| SCHEMBL4423447 | 0.91 | GHSR (0.63) | GHSRCTSBCTSSCTSKPTPN1 | |
| SCHEMBL4423444 | 0.91 | GHSR (0.63) | GHSRCTSBCTSSCTSKPTPN1 | |
| SCHEMBL6319895 | 0.88 | GHSR (0.56) | GHSRCTSBCTSSCTSKCTSL | |
| SCHEMBL6319848 | 0.88 | GHSR (0.56) | GHSRCTSBCTSSCTSKCTSL | |
| SCHEMBL6319905 | 0.88 | GHSR (0.56) | GHSRCTSBCTSSCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506969-B1 | Compounds with growth hormone releasing properties | HELSINN THERAPEUTICS US INC (US) | 2010-06-09 | — | — | EP | disclosed |
| EP-1506969-A1 | Compounds with growth hormone releasing properties | NOVO NORDISK A/S (DK) | 2005-02-16 | — | — | EP | disclosed |
| EP-1047709-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-11-03 | — | — | EP | disclosed |
| US-6083908-A | TREATING MEDICAL DISORDERS RESULTING FROM DEFICIENCY IN GROWTH HORMONE | NOVO NORDISK A/S (DK) | 2000-07-04 | — | — | US | disclosed |